Table 3.

Percentage of S-Phase CD34+ Cells Purified From the BM and the PB of Normal Subjects Receiving rhG-CSF

Source of CellsPretreatment (%)Posttreatment (%)
CFU-GMBFU-ETotalCFU-GMBFU-ETotal
PB ND ND ND 8.2 ± 6.2 3.1 ± 4  4 ± 5 
BM 39.8 ± 10*† 17 ± 93-151 25.5 ± 123-151  52 ± 8*†  20 ± 123-151 34.6 ± 11*† 
Source of CellsPretreatment (%)Posttreatment (%)
CFU-GMBFU-ETotalCFU-GMBFU-ETotal
PB ND ND ND 8.2 ± 6.2 3.1 ± 4  4 ± 5 
BM 39.8 ± 10*† 17 ± 93-151 25.5 ± 123-151  52 ± 8*†  20 ± 123-151 34.6 ± 11*† 

The results are expressed as the mean ± SD of 16 and 10 different experiments from PB and BM samples, respectively. S-phase progenitors were evaluated before and after rhG-CSF treatment by the Ara-C suicide test.

Abbreviation: ND, not done.

F3-150

Statistically significant (P < .05) compared with pretreatment values.

F3-151

Statistically significant (P < .05) compared with PB CD34+ cells.

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