Table 2.

Effects of Epo on Ca2+ Channels in Human Erythroblasts

ControlEpo
Unitary current, pA 0.197 ± 0.005 0.206 ± 0.010 
Mean open time, ms 4.27 ± 0.75 11.15 ± 1.80* 
Open probability, % 0.26 ± 0.06 2.56 ± 0.59* 
No. of observations 
ControlEpo
Unitary current, pA 0.197 ± 0.005 0.206 ± 0.010 
Mean open time, ms 4.27 ± 0.75 11.15 ± 1.80* 
Open probability, % 0.26 ± 0.06 2.56 ± 0.59* 
No. of observations 

Recordings of single channels in day 10 BFU-E–derived erythroblasts were obtained at 29°C and Vp-20 mV as described in Materials and Methods. Ba2+ (30 mmol/L) was the charge carrier for Ca2+ channels. Mean ± SEM are shown.

*

P < .02 compared with control.

Close Modal

or Create an Account

Close Modal
Close Modal