Evidence of Increased Proliferative Activity of the Primitive Human CFC Present in NOD/SCID Mice 4 Weeks After Their Transplantation With 2 × 107 Normal Human Marrow Cells
| . | . | % in S-Phase . | |
|---|---|---|---|
| . | . | Human Cells in Mice . | Normal Human Marrow3-150 . |
| CFU-E | (1-2 clusters/colony) | 68 ± 6 | 43 ± 2 |
| Mature BFU-E | (3-8 clusters/colony) | 58 ± 7 | 37 ± 2 |
| Mature CFU-GM | (<500 cells/colony) | 51 ± 2 | 37 ± 3 |
| Primitive BFU-E | (>8 clusters/colony) | 69 ± 4 | 14 ± 2 |
| Primitive CFU-GM | (>500 cells/colony) | 57 ± 5 | 4 ± 2 |
| . | . | % in S-Phase . | |
|---|---|---|---|
| . | . | Human Cells in Mice . | Normal Human Marrow3-150 . |
| CFU-E | (1-2 clusters/colony) | 68 ± 6 | 43 ± 2 |
| Mature BFU-E | (3-8 clusters/colony) | 58 ± 7 | 37 ± 2 |
| Mature CFU-GM | (<500 cells/colony) | 51 ± 2 | 37 ± 3 |
| Primitive BFU-E | (>8 clusters/colony) | 69 ± 4 | 14 ± 2 |
| Primitive CFU-GM | (>500 cells/colony) | 57 ± 5 | 4 ± 2 |
Results from previously published studies using the same procedures.32 38