Genotype Analysis of E9-E9.5 Embryos and 2-Week-Old Mice Generated From GATA-2+/−/p53+/− Compound Heterozygous Mice
G2 . | p53 . | No. . | Observed (%) . | Expected (%) . |
---|---|---|---|---|
E9-E9.5 embryos | ||||
+/+ | +/+ | 2 | 5.3 | 6.25 |
+/+ | +/− | 4 | 10.5 | 12.5 |
+/+ | −/− | 1 | 2.6 | 6.25 |
+/− | +/+ | 6 | 15.8 | 12.5 |
+/− | +/− | 13 | 34.2 | 25 |
+/− | −/− | 6 | 15.8 | 12.5 |
−/− | +/+ | 1 | 2.6 | 6.25 |
−/− | +/− | 3 | 7.9 | 12.5 |
−/− | −/− | 2 | 5.3 | 6.25 |
Total | 38 | 100 | 100 | |
2-Week-old mice | ||||
+/+ | +/+ | 10 | 18.9 | 6.25 |
+/+ | +/− | 9 | 17.0 | 12.5 |
+/+ | −/− | 2 | 3.8 | 6.25 |
+/− | +/+ | 12 | 22.6 | 12.5 |
+/− | +/− | 17 | 32.1 | 25 |
+/− | −/− | 3 | 5.6 | 12.5 |
−/− | +/+ | 0 | 0 | 6.25 |
−/− | +/− | 0 | 0 | 12.5 |
−/− | −/− | 0 | 0 | 6.25 |
Total | 53 | 100 | 100 |
G2 . | p53 . | No. . | Observed (%) . | Expected (%) . |
---|---|---|---|---|
E9-E9.5 embryos | ||||
+/+ | +/+ | 2 | 5.3 | 6.25 |
+/+ | +/− | 4 | 10.5 | 12.5 |
+/+ | −/− | 1 | 2.6 | 6.25 |
+/− | +/+ | 6 | 15.8 | 12.5 |
+/− | +/− | 13 | 34.2 | 25 |
+/− | −/− | 6 | 15.8 | 12.5 |
−/− | +/+ | 1 | 2.6 | 6.25 |
−/− | +/− | 3 | 7.9 | 12.5 |
−/− | −/− | 2 | 5.3 | 6.25 |
Total | 38 | 100 | 100 | |
2-Week-old mice | ||||
+/+ | +/+ | 10 | 18.9 | 6.25 |
+/+ | +/− | 9 | 17.0 | 12.5 |
+/+ | −/− | 2 | 3.8 | 6.25 |
+/− | +/+ | 12 | 22.6 | 12.5 |
+/− | +/− | 17 | 32.1 | 25 |
+/− | −/− | 3 | 5.6 | 12.5 |
−/− | +/+ | 0 | 0 | 6.25 |
−/− | +/− | 0 | 0 | 12.5 |
−/− | −/− | 0 | 0 | 6.25 |
Total | 53 | 100 | 100 |