Increased M-CSF Receptor Levels on Macrophages Generated From Monocyte Cultured With M-CSF + IL-10
| . | 125I-M-CSF Specific Binding (CPM/105 cells) . | |
|---|---|---|
| . | M-CSF . | M-CSF + IL-10 . |
| Exp. 1 | 4,254 | 6,964 |
| Exp. 2 | 3,400 | 6,588 |
| Exp. 3 | 2,903 | 4,848 |
| . | 125I-M-CSF Specific Binding (CPM/105 cells) . | |
|---|---|---|
| . | M-CSF . | M-CSF + IL-10 . |
| Exp. 1 | 4,254 | 6,964 |
| Exp. 2 | 3,400 | 6,588 |
| Exp. 3 | 2,903 | 4,848 |
Monocytes were incubated with rhM-CSF (50 ng/mL) plus IL-10 (25 ng/mL) or M-CSF alone for 1 week, then 125I-M-CSF binding was assessed as described in Materials and Methods. Data are results from three independent experiments.