Table 2.

Pathologic Assessment of End-Organs After Guinea Pigs Received AT 24 Hours Postinfusion of DIC-SA

Gross HemorrhageAbscess FormationMortalityHistopathology (fibrin formation)Normal Histology
DIC-SA (n = 4) 
DIC-SA + AT concentrate 
500 IU/kg (n = 4) 0* 
1,000 IU/kg (n = 8) 0 
Gross HemorrhageAbscess FormationMortalityHistopathology (fibrin formation)Normal Histology
DIC-SA (n = 4) 
DIC-SA + AT concentrate 
500 IU/kg (n = 4) 0* 
1,000 IU/kg (n = 8) 0 
*

Significantly different from DIC-SA alone group (P ≤ .05).

Significantly different from DIC-SA alone group (P ≤ .025).

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