International Lymphoma Study Group Classification (including provisional categories)
| B-Cell Lymphoma . | T/NK-Cell Lymphoma . | Others . |
|---|---|---|
| Precursor B-lymphoblastic | Precursor T-lymphoblastic | Composite lymphoma (types specified)† |
| Small lymphocytic (CLL) | T-cell chronic lymphocytic leukemia | Malignant lymphoma, unclassifiable low grade |
| Lymphoplasmacytic | Large granular lymphocyte leukemia | Malignant lymphoma unclassifiable high grade |
| Mantle cell | Mycosis fungoides | Malignant lymphoma, unclassifiable |
| Follicle center, follicular | Peripheral T cell, unspecified | |
| Grade 1* | Medium-sized | Hodgkin's disease |
| Grade 2* | Mixed medium and large cell | Diagnosis other than lymphoma |
| Grade 3* | Large cell | Case unclassifiable |
| Follicle center diffuse, small cell | Lymphoepithelioid | |
| Marginal zone B-cell, MALT type | Hepatosplenic | |
| Marginal zone B-cell, nodal | Subcutaneous panniculitic | |
| Marginal zone B-cell, splenic | Angioimmunoblastic | |
| Hairy cell leukemia | Angiocentric, nasal | |
| Plasmacytoma | Intestinal | |
| Diffuse large B-cell | Adult T-cell lymphoma/leukemia | |
| Diffuse mediastinal large B-cell | Anaplastic large cell (including null phenotype) | |
| Burkitt's | Anaplastic large cell, Hodgkin's-like | |
| High grade B-cell, Burkitt-like | Unclassifiable low grade | |
| Unclassifiable low grade | Unclassifiable high grade | |
| Unclassifiable high grade |
| B-Cell Lymphoma . | T/NK-Cell Lymphoma . | Others . |
|---|---|---|
| Precursor B-lymphoblastic | Precursor T-lymphoblastic | Composite lymphoma (types specified)† |
| Small lymphocytic (CLL) | T-cell chronic lymphocytic leukemia | Malignant lymphoma, unclassifiable low grade |
| Lymphoplasmacytic | Large granular lymphocyte leukemia | Malignant lymphoma unclassifiable high grade |
| Mantle cell | Mycosis fungoides | Malignant lymphoma, unclassifiable |
| Follicle center, follicular | Peripheral T cell, unspecified | |
| Grade 1* | Medium-sized | Hodgkin's disease |
| Grade 2* | Mixed medium and large cell | Diagnosis other than lymphoma |
| Grade 3* | Large cell | Case unclassifiable |
| Follicle center diffuse, small cell | Lymphoepithelioid | |
| Marginal zone B-cell, MALT type | Hepatosplenic | |
| Marginal zone B-cell, nodal | Subcutaneous panniculitic | |
| Marginal zone B-cell, splenic | Angioimmunoblastic | |
| Hairy cell leukemia | Angiocentric, nasal | |
| Plasmacytoma | Intestinal | |
| Diffuse large B-cell | Adult T-cell lymphoma/leukemia | |
| Diffuse mediastinal large B-cell | Anaplastic large cell (including null phenotype) | |
| Burkitt's | Anaplastic large cell, Hodgkin's-like | |
| High grade B-cell, Burkitt-like | Unclassifiable low grade | |
| Unclassifiable low grade | Unclassifiable high grade | |
| Unclassifiable high grade |
Provisional categories are indicated in italic type.
Abbreviations: CLL, chronic lymphocytic leukemia; MALT, mucosal-associated lymphoid tissue.
Follicular lymphomas are designated as such and were graded according to the Berard method.90
Composite lymphomas consisted of two distinctly different cytologic subtypes of lymphoma.
Data from Harris et al.84