Percentage of Histamine Release After Intradermal Injection of MCP-1 and RANTES
Treatment
.
.
P<
.
PBS (control)
ND
—
FMLP 10−6 mol/L
30 ± 5
—
LPS 10 ng
42 ± 8
—
MCP-1 10 ng
20 ± 3
(*)
MCP-1 20 ng
25 ± 6
(**)
RANTES 10 ng
34 ± 5
.05
RANTES 20 ng
40 ± 7
.05
Treatment
.
.
P<
.
PBS (control)
ND
—
FMLP 10−6 mol/L
30 ± 5
—
LPS 10 ng
42 ± 8
—
MCP-1 10 ng
20 ± 3
(*)
MCP-1 20 ng
25 ± 6
(**)
RANTES 10 ng
34 ± 5
.05
RANTES 20 ng
40 ± 7
.05
Percent release of total histamine by a 50 μL intradermal injection in skin tissue treated with PBS, FMLP, LPS, MCP-1, and RANTES. P values were calculated comparing MCP-1 10 ng (*) with RANTES 10 ng and MCP-1 20 ng (**) with RANTES 20 ng.