Table 3.

Percentage of Histamine Release After Intradermal Injection of MCP-1 and RANTES

TreatmentP<
PBS (control) ND  —  
FMLP 10−6 mol/L 30 ± 5  —  
LPS 10 ng 42 ± 8  —  
MCP-1 10 ng 20 ± 3 (*) 
MCP-1 20 ng 25 ± 6 (**) 
RANTES 10 ng 34 ± 5 .05 
RANTES 20 ng 40 ± 7 .05 
TreatmentP<
PBS (control) ND  —  
FMLP 10−6 mol/L 30 ± 5  —  
LPS 10 ng 42 ± 8  —  
MCP-1 10 ng 20 ± 3 (*) 
MCP-1 20 ng 25 ± 6 (**) 
RANTES 10 ng 34 ± 5 .05 
RANTES 20 ng 40 ± 7 .05 

Percent release of total histamine by a 50 μL intradermal injection in skin tissue treated with PBS, FMLP, LPS, MCP-1, and RANTES. P values were calculated comparing MCP-1 10 ng (*) with RANTES 10 ng and MCP-1 20 ng (**) with RANTES 20 ng.

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