Table 1. Patient Characteristics and... | American Society of Hematology

Table 1.

Patient Characteristics and Transduction Data

Patient	Age/Sex	Cell Source	Vector	CD34 Cells	CFU-C Transduction Efficiency %^*	Transplant Date	Status
				Infused/kg
				(millions)

6H	57/M	PB	G1Na	1.46	19	6/20/95	Alive/CR
MM 1		PB	None	9.05
		BM	LNL6	0.20	8
		BM	None	0.81
6H	44/M	PB	G1Na	0.08	>1	4/7/94	Alive/PR
MM 2		PB	None	0.80
		BM	LNL6	0.75	ND
		BM	None	0.75
6H	54/M	PB	G1Na	0.01	1	11/18/94	Alive/PR
MM 3		PB	None	1.63
		BM	LNL6	0.07	0
		BM	None	0.02
6H	45/F	PB	LNL6	4.61	>0	10/11/94	Alive/CR
BC 4		PB	None	19.29
		BM	G1Na	0.18	2
		BM	None	4.00
6H	53/F	PB	LNL6	0.80	ND	10/12/95	Alive/PD Day 111
BC 5		PB	None	3.40
		BM	G1Na	0.11	ND
		BM	None	1.00
ST	46/M	PB	LNL6	0.07	20	6/24/94	Alive/PR
MM 1		PB	None	1.03
		BM	G1Na	0.00	2
		BM	None	0.36
ST	48/M	PB	G1Na	1.12	0	6/10/94	Alive/PR
MM 2		PB	None	27.55
		BM	LNL6	0.15	10
		BM	None	1.69
ST	49/F	PB	LNL6	0.09	ND	2/29/96	Alive/PR
BC 3		PB	None	0.72
		BM	G1Na	0.18	30
		BM	None	6.63
ST	36/F	PB	G1Na	0.32	36	3/12/96	Alive/PD Day 123
BC 4		PB	None	1.10
		BM	LNL6	0.37	ND
		BM	None	4.31

Patient	Age/Sex	Cell Source	Vector	CD34 Cells	CFU-C Transduction Efficiency %^*	Transplant Date	Status
				Infused/kg
				(millions)

6H	57/M	PB	G1Na	1.46	19	6/20/95	Alive/CR
MM 1		PB	None	9.05
		BM	LNL6	0.20	8
		BM	None	0.81
6H	44/M	PB	G1Na	0.08	>1	4/7/94	Alive/PR
MM 2		PB	None	0.80
		BM	LNL6	0.75	ND
		BM	None	0.75
6H	54/M	PB	G1Na	0.01	1	11/18/94	Alive/PR
MM 3		PB	None	1.63
		BM	LNL6	0.07	0
		BM	None	0.02
6H	45/F	PB	LNL6	4.61	>0	10/11/94	Alive/CR
BC 4		PB	None	19.29
		BM	G1Na	0.18	2
		BM	None	4.00
6H	53/F	PB	LNL6	0.80	ND	10/12/95	Alive/PD Day 111
BC 5		PB	None	3.40
		BM	G1Na	0.11	ND
		BM	None	1.00
ST	46/M	PB	LNL6	0.07	20	6/24/94	Alive/PR
MM 1		PB	None	1.03
		BM	G1Na	0.00	2
		BM	None	0.36
ST	48/M	PB	G1Na	1.12	0	6/10/94	Alive/PR
MM 2		PB	None	27.55
		BM	LNL6	0.15	10
		BM	None	1.69
ST	49/F	PB	LNL6	0.09	ND	2/29/96	Alive/PR
BC 3		PB	None	0.72
		BM	G1Na	0.18	30
		BM	None	6.63
ST	36/F	PB	G1Na	0.32	36	3/12/96	Alive/PD Day 123
BC 4		PB	None	1.10
		BM	LNL6	0.37	ND
		BM	None	4.31

Bold type indicates that all mononuclear cells, not just CD34⁺ cells, were infused.

Abbreviations: MM, multiple myeloma; BC, breast cancer; PR, partial remission; CR, complete remission; PD, progressive disease; CFU-C, colony-forming unit cell.

% Neomycin resistant CFU-C assayed at the end of transduction.

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