Table 1.

Effect of PTX (1 μg/mL, 2.5 Hours at 37°C) on Eosinophil Aggregation Induced by PAF, C5a, and LTB4

Aggregation
(% maximal response induced by PMA)
ControlPTX
PAF (10−8 mol/L) 16.3 ± 4.2 13.3 ± 5.2 
C5a (10−7 mol/L) 24.8 ± 2.5 0* 
LTB4 (10−8 mol/L) 20.5 ± 1.2 5.0 ± 2.0* 
Aggregation
(% maximal response induced by PMA)
ControlPTX
PAF (10−8 mol/L) 16.3 ± 4.2 13.3 ± 5.2 
C5a (10−7 mol/L) 24.8 ± 2.5 0* 
LTB4 (10−8 mol/L) 20.5 ± 1.2 5.0 ± 2.0* 

Values are the mean ± SEM of three to four experiments.

*

P < .01 when compared with control values.

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