Clinical Details of the Patients
| . | Sibling Donor . | VUD . | Total . |
|---|---|---|---|
| No. of patients | 50 | 16 | 66 |
| Sex | |||
| Male | 25 | 10 | 35 |
| Female | 25 | 6 | 31 |
| Age at transplantation | |||
| <20 yr | 4 | 1 | 5 |
| 20-40 yr | 32 | 10 | 42 |
| >40 yr | 14 | 5 | 19 |
| Diagnosis | |||
| Chronic myeloid leukemia | 44 | 16 | 60 |
| Acute lymphoblastic leukemia | 1 | 0 | 1 |
| Acute myeloid leukemia | 4 | 0 | 4 |
| Myelodysplastic syndrome | 1 | 0 | 1 |
| Conditioning regimen | |||
| Cyclophosphamide + total body irradiation | 49 | 15 | 64 |
| Cyclophosphamide + busulphan | 1 | 1 | 2 |
| Graft-versus-host disease prophylaxis | |||
| Cyclosporin + steroids | 2 | 0 | 2 |
| Cyclosporin + methotrexate | 44 | 1 | 45 |
| In vivo or ex vivo T-cell depletion | 4 | 15 | 19 |
| Acute graft-versus-host disease | |||
| Grade 0-I | 31 | 6 | 37 |
| Grade II-IV | 17 | 10 | 27 |
| Unknown/not evaluable | 2 | 0 | 2 |
| Chronic graft-versus-host disease | |||
| Yes | 25 | 11 | 36 |
| No | 19 | 5 | 24 |
| Unknown/not evaluable | 6 | 0 | 6 |
| . | Sibling Donor . | VUD . | Total . |
|---|---|---|---|
| No. of patients | 50 | 16 | 66 |
| Sex | |||
| Male | 25 | 10 | 35 |
| Female | 25 | 6 | 31 |
| Age at transplantation | |||
| <20 yr | 4 | 1 | 5 |
| 20-40 yr | 32 | 10 | 42 |
| >40 yr | 14 | 5 | 19 |
| Diagnosis | |||
| Chronic myeloid leukemia | 44 | 16 | 60 |
| Acute lymphoblastic leukemia | 1 | 0 | 1 |
| Acute myeloid leukemia | 4 | 0 | 4 |
| Myelodysplastic syndrome | 1 | 0 | 1 |
| Conditioning regimen | |||
| Cyclophosphamide + total body irradiation | 49 | 15 | 64 |
| Cyclophosphamide + busulphan | 1 | 1 | 2 |
| Graft-versus-host disease prophylaxis | |||
| Cyclosporin + steroids | 2 | 0 | 2 |
| Cyclosporin + methotrexate | 44 | 1 | 45 |
| In vivo or ex vivo T-cell depletion | 4 | 15 | 19 |
| Acute graft-versus-host disease | |||
| Grade 0-I | 31 | 6 | 37 |
| Grade II-IV | 17 | 10 | 27 |
| Unknown/not evaluable | 2 | 0 | 2 |
| Chronic graft-versus-host disease | |||
| Yes | 25 | 11 | 36 |
| No | 19 | 5 | 24 |
| Unknown/not evaluable | 6 | 0 | 6 |