Table 4. Vβ TCR Repertoire Reported in... | American Society of Hematology

Table 4.

Vβ TCR Repertoire Reported in CTCL and Autoimmune Diseases

Disease	Author	Methods	Patients	Site	Vβ Dominant
CTCL	Hunt et al60	7 MoAbs	13	Skin	Vβ 5
CTCL	Jack et al39	2 MoAbs	16	Skin/tumor	Vβ 8
CTCL	Lessin et al43	RNA-PCR assay	1	PBL	Vβ 6.4
MF	Wood et al40	RNA-PCR assay	1	Skin	Multiple with Vβ 6 dominant
MF	Bahler et al41	RNA-PCR assay	28	Skin	Multiple families with Vβ 6 & 8 dominant
SS	Kono et al61	RNA-PCR assay	19	PBL	Multiple with Vβ 8
CTCL	Longley et al44	RNA-PCR assay + Abs	6	PBL	Polyclonal random
SS	Gorochov et al42	RNA-PCR assay	16	Skin	Vβ 5, 6, 8, 13, 18
RA	Paliard et al62	RNA-PCR assay	6	Skin/PBL	Multiple with Vβ 14 dominant
RA	Howell et al63	RNA-PCR assay	5	Synovial fluid	Multiple with Vβ 14, 17 dominant
RA	Bucht et al64	RNA-PCR assay	9	Synovial fluid	Random
Psoriasis	Chang et al52	RNA-PCR assay	8	Skin/PBL	Multiple with Vβ 3, 13.1 dominant
Kawasaki	Abe et al5	RNA-PCR assay + Abs	19	PBL	Multiple with Vβ 2, 8 dominant

Disease	Author	Methods	Patients	Site	Vβ Dominant
CTCL	Hunt et al60	7 MoAbs	13	Skin	Vβ 5
CTCL	Jack et al39	2 MoAbs	16	Skin/tumor	Vβ 8
CTCL	Lessin et al43	RNA-PCR assay	1	PBL	Vβ 6.4
MF	Wood et al40	RNA-PCR assay	1	Skin	Multiple with Vβ 6 dominant
MF	Bahler et al41	RNA-PCR assay	28	Skin	Multiple families with Vβ 6 & 8 dominant
SS	Kono et al61	RNA-PCR assay	19	PBL	Multiple with Vβ 8
CTCL	Longley et al44	RNA-PCR assay + Abs	6	PBL	Polyclonal random
SS	Gorochov et al42	RNA-PCR assay	16	Skin	Vβ 5, 6, 8, 13, 18
RA	Paliard et al62	RNA-PCR assay	6	Skin/PBL	Multiple with Vβ 14 dominant
RA	Howell et al63	RNA-PCR assay	5	Synovial fluid	Multiple with Vβ 14, 17 dominant
RA	Bucht et al64	RNA-PCR assay	9	Synovial fluid	Random
Psoriasis	Chang et al52	RNA-PCR assay	8	Skin/PBL	Multiple with Vβ 3, 13.1 dominant
Kawasaki	Abe et al5	RNA-PCR assay + Abs	19	PBL	Multiple with Vβ 2, 8 dominant

Abbreviations: MoAbs, monoclonal antibodies; Abs, antibodies; PBL, peripheral blood lymphocytes.