Variant counts identified in bulk tumor population and SC exomes
| Variants called* . | Nonsynonymous SNV . | Synonymous SNV . | Stopgain SNV . | Frameshift insertion . | Frameshift deletion . | Total . |
|---|---|---|---|---|---|---|
| Bulk tumor exome | 20 | 14 | 1 | 9 | 3 | 48 |
| In 1 or more SCs | 16 | 10 | 1 | 6 | 1 | 34 |
| Not in 1 or more SCs | 4 | 4 | 0 | 4 | 2 | 14 |
| Total in 2 or more SCs | 28 | 16 | 3 | 3 | 1 | 51 |
| In bulk tumor | 16 | 9 | 1 | 3 | 1 | 30 |
| Not in bulk tumor | 12 | 7 | 2 | 0 | 0 | 21 |
| Total unique variants | 32 | 21 | 3 | 10 | 3 | 69 |
| Variants called* . | Nonsynonymous SNV . | Synonymous SNV . | Stopgain SNV . | Frameshift insertion . | Frameshift deletion . | Total . |
|---|---|---|---|---|---|---|
| Bulk tumor exome | 20 | 14 | 1 | 9 | 3 | 48 |
| In 1 or more SCs | 16 | 10 | 1 | 6 | 1 | 34 |
| Not in 1 or more SCs | 4 | 4 | 0 | 4 | 2 | 14 |
| Total in 2 or more SCs | 28 | 16 | 3 | 3 | 1 | 51 |
| In bulk tumor | 16 | 9 | 1 | 3 | 1 | 30 |
| Not in bulk tumor | 12 | 7 | 2 | 0 | 0 | 21 |
| Total unique variants | 32 | 21 | 3 | 10 | 3 | 69 |
SNV, single-nucleotide variant.
Variant counts of each type are tabulated for the bulk tumor and SC exomes. For the SC exomes, selection criteria required that the variant be present in 2 or more SC cells to be counted. The number of variants identified in 2 or more SC exomes that were also called (n = 30) or not called (n = 21) in the bulk tumor exome are also given.