Best response on combination therapy
| Population . | Best clinical response, n (%) [95% CI] . | ||||
|---|---|---|---|---|---|
| CR . | PR . | SD . | PD . | ORR* . | |
| Overall, N = 53 | 39 (73.6) [59.7, 84.7] | 10 (18.9) | 3 (5.7) | 1 (1.9) | 49 (92.5) [81.8, 97.9] |
| Response to frontline therapy | |||||
| Primary refractory, n = 28 | 18 (64.3) [44.1, 81.4] | 6 (21.4) | 3 (10.7) | 1 (3.6) | 24 (85.7) [67.3, 96.0] |
| Relapsed, n = 25 | 21 (84.0) [63.9, 95.5] | 4 (16.0) | 0 (0.0) | 0 (0.0) | 25 (100) [86.3, 100] |
| ASCT | |||||
| Yes, n = 40 | 34 (85.0) [70.2, 94.3] | 4 (10.0) | 2 (5.0) | 0 (0.0) | 38 (95.0) [83.1, 99.4] |
| No, n = 13 | 5 (38.5) [13.9, 68.4] | 6 (46.2) | 1 (7.7) | 1 (7.7) | 11 (84.6) [54.6, 98.1] |
| Population . | Best clinical response, n (%) [95% CI] . | ||||
|---|---|---|---|---|---|
| CR . | PR . | SD . | PD . | ORR* . | |
| Overall, N = 53 | 39 (73.6) [59.7, 84.7] | 10 (18.9) | 3 (5.7) | 1 (1.9) | 49 (92.5) [81.8, 97.9] |
| Response to frontline therapy | |||||
| Primary refractory, n = 28 | 18 (64.3) [44.1, 81.4] | 6 (21.4) | 3 (10.7) | 1 (3.6) | 24 (85.7) [67.3, 96.0] |
| Relapsed, n = 25 | 21 (84.0) [63.9, 95.5] | 4 (16.0) | 0 (0.0) | 0 (0.0) | 25 (100) [86.3, 100] |
| ASCT | |||||
| Yes, n = 40 | 34 (85.0) [70.2, 94.3] | 4 (10.0) | 2 (5.0) | 0 (0.0) | 38 (95.0) [83.1, 99.4] |
| No, n = 13 | 5 (38.5) [13.9, 68.4] | 6 (46.2) | 1 (7.7) | 1 (7.7) | 11 (84.6) [54.6, 98.1] |
ORR, objective response rate. Other abbreviations are explained in Table 1.
CR plus PR.