Table 5.

Notable prospective clinical trials using checkpoint blockade before or after allogeneic transplant

Clinical trialTitle
NCT02981914 Pilot Study of Pembrolizumab Treatment for Disease Relapse after Allogeneic Stem Cell Transplantation 
NCT02985554 Phase I Study to Assess the Tolerability and Efficacy of Nivolumab in Patients with Hematologic Malignancies 
NCT03286114 Augmentation of the Graft vs Leukemia Effect via Checkpoint Blockade with Pembrolizumab 
NCT02846376 Single Agent and Combined Inhibition after Allogeneic Stem Cell Transplant (CPIT-002) 
NCT03146468 Nivolumab for Relapsed or Residual Haematologic Malignancies after Allogeneic Stem Cell Transplantation (NIVALLO) 
NCT03200977 Safety of Allogeneic Hematopoietic Cell Transplantation (HCT) for Patients with Classical Hodgkin Lymphoma (CHL) Treated with Nivolumab 
NCT01822509 Ipilimumab or Nivolumab in Treating Patients with Relapsed Hematologic Malignancies after Donor Stem Cell Transplant 
NCT02603419 Avelumab in Patients with Previously Treated Advanced Stage Classical Hodgkin's Lymphoma (JAVELIN HODGKINS) 
Clinical trialTitle
NCT02981914 Pilot Study of Pembrolizumab Treatment for Disease Relapse after Allogeneic Stem Cell Transplantation 
NCT02985554 Phase I Study to Assess the Tolerability and Efficacy of Nivolumab in Patients with Hematologic Malignancies 
NCT03286114 Augmentation of the Graft vs Leukemia Effect via Checkpoint Blockade with Pembrolizumab 
NCT02846376 Single Agent and Combined Inhibition after Allogeneic Stem Cell Transplant (CPIT-002) 
NCT03146468 Nivolumab for Relapsed or Residual Haematologic Malignancies after Allogeneic Stem Cell Transplantation (NIVALLO) 
NCT03200977 Safety of Allogeneic Hematopoietic Cell Transplantation (HCT) for Patients with Classical Hodgkin Lymphoma (CHL) Treated with Nivolumab 
NCT01822509 Ipilimumab or Nivolumab in Treating Patients with Relapsed Hematologic Malignancies after Donor Stem Cell Transplant 
NCT02603419 Avelumab in Patients with Previously Treated Advanced Stage Classical Hodgkin's Lymphoma (JAVELIN HODGKINS) 
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