Summary of baseline characteristics
| Parameter . | Adults (n = 9) . | Children (n = 5) . | Combined (N = 14) . |
|---|---|---|---|
| Age, y | |||
| Mean (SD) | 31.9 (7.56) | 10.8 (5.26) | 24.4 (12.39) |
| Median | 33.0 | 11.0 | 24.0 |
| Min, max | 20, 42 | 5, 16 | 5, 42 |
| Sex, n (%) | |||
| Male | 3 (33) | 1 (20) | 4 (29) |
| Female | 6 (67) | 4 (80) | 10 (71) |
| Baseline plasminogen activity, n (%) | |||
| 0% to 10% | 3 (33) | 0 | 3 (21) |
| 11% to 20% | 1 (11) | 2 (40) | 3 (21) |
| 21% to 30% | 3 (33) | 3 (60) | 6 (43) |
| 31% to 40% | 1 (11) | 0 | 1 (7) |
| 41% to 45% | 1 (11) | 0 | 1 (7) |
| >45% | 0 | 0 | 0 |
| Site of clinical manifestations, n (%) | |||
| Any* | 8 (89) | 3 (60) | 11 (79) |
| Conjunctiva | 6 (67) | 2 (40) | 8 (57) |
| Gingiva | 3 (33) | 0 | 3 (21) |
| Abnormal wound healing | 3 (33) | 0 | 3 (21) |
| Bronchus | 2 (22) | 0 | 2 (14) |
| Colon | 0 | 2 (40) | 2 (14) |
| Cervix | 2 (22) | 0 | 2 (14) |
| Vagina | 0 | 2 (40) | 2 (14) |
| Nasopharynx | 1 (11) | 0 | 1 (7) |
| Kidney | 1 (11) | 0 | 1 (7) |
| Multisystem | 6 (67) | 3 (60) | 9 (64) |
| Parameter . | Adults (n = 9) . | Children (n = 5) . | Combined (N = 14) . |
|---|---|---|---|
| Age, y | |||
| Mean (SD) | 31.9 (7.56) | 10.8 (5.26) | 24.4 (12.39) |
| Median | 33.0 | 11.0 | 24.0 |
| Min, max | 20, 42 | 5, 16 | 5, 42 |
| Sex, n (%) | |||
| Male | 3 (33) | 1 (20) | 4 (29) |
| Female | 6 (67) | 4 (80) | 10 (71) |
| Baseline plasminogen activity, n (%) | |||
| 0% to 10% | 3 (33) | 0 | 3 (21) |
| 11% to 20% | 1 (11) | 2 (40) | 3 (21) |
| 21% to 30% | 3 (33) | 3 (60) | 6 (43) |
| 31% to 40% | 1 (11) | 0 | 1 (7) |
| 41% to 45% | 1 (11) | 0 | 1 (7) |
| >45% | 0 | 0 | 0 |
| Site of clinical manifestations, n (%) | |||
| Any* | 8 (89) | 3 (60) | 11 (79) |
| Conjunctiva | 6 (67) | 2 (40) | 8 (57) |
| Gingiva | 3 (33) | 0 | 3 (21) |
| Abnormal wound healing | 3 (33) | 0 | 3 (21) |
| Bronchus | 2 (22) | 0 | 2 (14) |
| Colon | 0 | 2 (40) | 2 (14) |
| Cervix | 2 (22) | 0 | 2 (14) |
| Vagina | 0 | 2 (40) | 2 (14) |
| Nasopharynx | 1 (11) | 0 | 1 (7) |
| Kidney | 1 (11) | 0 | 1 (7) |
| Multisystem | 6 (67) | 3 (60) | 9 (64) |
Max, maximum; min, minimum.
Three patients (2 children and 1 adult) had no clinical manifestations at baseline.