CAR targets in hematological malignancies
| Malignancy . | CAR targets . |
|---|---|
| B cell | CD19, CD20, CD22 |
| Myeloma | BCMA, CD38, CD56, CD138, CS-1, integrin β7, Κ light chain, Lewis Y |
| Myeloid leukemia | CD33, CD44v6, CD38, CD70, CD123, CLEC12A, EMR2, FOLR2, Lewis Y, Tim3 |
| T-ALL/ lymphoma | TRBC1, CCR4, CD7 |
| Malignancy . | CAR targets . |
|---|---|
| B cell | CD19, CD20, CD22 |
| Myeloma | BCMA, CD38, CD56, CD138, CS-1, integrin β7, Κ light chain, Lewis Y |
| Myeloid leukemia | CD33, CD44v6, CD38, CD70, CD123, CLEC12A, EMR2, FOLR2, Lewis Y, Tim3 |
| T-ALL/ lymphoma | TRBC1, CCR4, CD7 |
T-ALL, T-cell acute lymphoblastic leukemia.