Human NK-cell receptors and their ligands
| Receptor . | Ligand . |
|---|---|
| Inhibitory receptors | |
| KIR2DL1 | C2 HLA-C |
| KIR2DL2 | C1 HLA-C |
| KIR2DL3 | C1 HLA-C |
| KIR2DL4 | HLA-G |
| KIR2DL5 | Not known |
| KIR3DL1 | Bw4 HLA-A and -B |
| KIR3DL2 | HLA-A3 and -A11 |
| KIR3DL3 | Not known |
| NKG2A | HLA-E |
| LIR-1 | HLA class I |
| Activating receptors | |
| KIR2DS1 | C2 HLA-C |
| KIR2DS2 | HLA-A11 |
| KIR2DS3 | Not known |
| KIR2DS4 | HLA-A11 |
| KIR2DS5 | C2 HLA-C |
| KIR3DS1 | HLA-F |
| NKG2C | HLA-E |
| NKG2D | MICA, MICB, ULBP1-4 |
| CD16 | IgG 1, 3, 4 |
| NKp30 | B7-H6, BAT3, CMV pp65 |
| NKp44 | Viral hemagglutinins |
| NKp46 | Viral hemagglutinins |
| NKp80 | AICL |
| CD160 | HLA-C |
| DNAM-1 | CD112, CD155 |
| CD96 | CD155, CD111 |
| 2B4 | CD48 |
| CRACC | CRACC |
| NTB-A | NTB-A |
| Receptor . | Ligand . |
|---|---|
| Inhibitory receptors | |
| KIR2DL1 | C2 HLA-C |
| KIR2DL2 | C1 HLA-C |
| KIR2DL3 | C1 HLA-C |
| KIR2DL4 | HLA-G |
| KIR2DL5 | Not known |
| KIR3DL1 | Bw4 HLA-A and -B |
| KIR3DL2 | HLA-A3 and -A11 |
| KIR3DL3 | Not known |
| NKG2A | HLA-E |
| LIR-1 | HLA class I |
| Activating receptors | |
| KIR2DS1 | C2 HLA-C |
| KIR2DS2 | HLA-A11 |
| KIR2DS3 | Not known |
| KIR2DS4 | HLA-A11 |
| KIR2DS5 | C2 HLA-C |
| KIR3DS1 | HLA-F |
| NKG2C | HLA-E |
| NKG2D | MICA, MICB, ULBP1-4 |
| CD16 | IgG 1, 3, 4 |
| NKp30 | B7-H6, BAT3, CMV pp65 |
| NKp44 | Viral hemagglutinins |
| NKp46 | Viral hemagglutinins |
| NKp80 | AICL |
| CD160 | HLA-C |
| DNAM-1 | CD112, CD155 |
| CD96 | CD155, CD111 |
| 2B4 | CD48 |
| CRACC | CRACC |
| NTB-A | NTB-A |