Table 1. WHO 2016 classification of... | American Society of Hematology

Table 1.

WHO 2016 classification of myeloid neoplasms with germ line predisposition

Myeloid neoplasm classification	Subtypes
Myeloid neoplasms with germ line predisposition without a preexisting disorder or organ dysfunction	AML with germ line CEBPA mutation; myeloid neoplasms with germ line DDX41 mutation*
Myeloid neoplasms with germ line predisposition and preexisting platelet disorders	Myloid neoplasms with germ line RUNX1 mutation; myeloid neoplasms with germ line ANKRD26* mutation; myeloid neoplasms with germ line ETV6* mutation*
Myeloid neoplasms with germ line predisposition and other organ dysfunction	Myeloid neoplsms with germ line GATA2 mutation; myeloid neoplasms associated with bone marrow failure syndromes; myeloid neoplasms associated with telomere biology disorders; JMML associated with neurofibromatosis, Noonan syndrome, or Noon syndrome–like disorders; myeloid neoplasms associated with Down syndrome*

Myeloid neoplasm classification	Subtypes
Myeloid neoplasms with germ line predisposition without a preexisting disorder or organ dysfunction	AML with germ line CEBPA mutation; myeloid neoplasms with germ line DDX41 mutation*
Myeloid neoplasms with germ line predisposition and preexisting platelet disorders	Myloid neoplasms with germ line RUNX1 mutation; myeloid neoplasms with germ line ANKRD26* mutation; myeloid neoplasms with germ line ETV6* mutation*
Myeloid neoplasms with germ line predisposition and other organ dysfunction	Myeloid neoplsms with germ line GATA2 mutation; myeloid neoplasms associated with bone marrow failure syndromes; myeloid neoplasms associated with telomere biology disorders; JMML associated with neurofibromatosis, Noonan syndrome, or Noon syndrome–like disorders; myeloid neoplasms associated with Down syndrome*

Modified from Arber et al.¹

AML, acute myeloid leukemia; JMML, juvenile myelomonocytic leukemia; WHO, World Health Organization.

Lymphoid neoplasms also reported.