Proposed hematologic response parameters with associated renal response and survival rates in patients with an initial dFLC <50 mg/L
| Hematologic response at 3 mo . | n (%) . | Renal response at 12 mo . | Overall survival at 63 mo, % . | Renal survival at 39 mo, % . |
|---|---|---|---|---|
| aCR | 20 (27) | 4 (21) | 94 | 100 |
| Low-dFLC PR | 29 (51) | 11 (85) | 93 | 100 |
| No response | 41 (39) | 8 (38) | 73 | 67 |
| Hematologic response at 3 mo . | n (%) . | Renal response at 12 mo . | Overall survival at 63 mo, % . | Renal survival at 39 mo, % . |
|---|---|---|---|---|
| aCR | 20 (27) | 4 (21) | 94 | 100 |
| Low-dFLC PR | 29 (51) | 11 (85) | 93 | 100 |
| No response | 41 (39) | 8 (38) | 73 | 67 |
Data are shown as counts (percentages of evaluable n). See “Methods” for definition of aCR. Organ response criteria were applied according to Gertz et al and Palladini et al.8,19
Low-dFLC PR, drop of dFLC to <10 mg/L if the initial dFLC was >20 mg/L (also counted in patients with aCR); No response, no aCR or low–dFLC PR, progress, start of second-line chemotherapy, or death.