Anti-CD20 mAbs in development
Name . | Company . | Type (all IgG1κ) . | Status . |
---|---|---|---|
Rituximab | Roche/Genentech | Chimeric | Approved |
Ofatumumab | Novartis | Fully human | Approved |
Obinutuzumab | Roche/Genentech | Humanized, glycoengineered | Approved |
Ublituximab | TG Therapeutics | Chimeric, glycoengineered | Phase 3 |
Veltuzumab | Immunomedics | Humanized | Phase 2 |
Ocaratuzumab | Mentrik Biotech | Humanized, Fc mutant | Apparently stopped |
Ocrelizumab | Roche/Genentech | Humanized | Stopped in hematology |
PRO131921 | Roche/Genentech | Humanized, Fc mutant | Stopped |
Name . | Company . | Type (all IgG1κ) . | Status . |
---|---|---|---|
Rituximab | Roche/Genentech | Chimeric | Approved |
Ofatumumab | Novartis | Fully human | Approved |
Obinutuzumab | Roche/Genentech | Humanized, glycoengineered | Approved |
Ublituximab | TG Therapeutics | Chimeric, glycoengineered | Phase 3 |
Veltuzumab | Immunomedics | Humanized | Phase 2 |
Ocaratuzumab | Mentrik Biotech | Humanized, Fc mutant | Apparently stopped |
Ocrelizumab | Roche/Genentech | Humanized | Stopped in hematology |
PRO131921 | Roche/Genentech | Humanized, Fc mutant | Stopped |