Table 2.

Comorbidities and impaired functional status

BV+DTIC (n = 22)BV+bendamustine (n = 20) n
Physical health (OARS)   
 ≥3 comorbidities OR ≥1 that significantly interfered with quality of life*, 11 (50) 9 (45) 
Physical function (MOS)   
 Limited a lot for ≥1 of 10 activities* 16 (73) 14 (70) 
 Preexisting PN 4 (25) 5 (36) 
 Patients with ≥1 fall within prior 6 mo 6 (29) 5 (26) 
 Preexisting PN 1 (17) 2 (40) 
Instrumental activities of daily living (OARS)   
 Completely dependent for ≥1 of 7 iADLs* 2 (9) 4 (20) 
Timed “up and go”   
 >13.5 s to complete action§ 9 (41) 14 (70) 
Unintentional weight loss of ≥10% within the past 6 mo 5 (23) 7 (35) 
BOMC test score of >6 7 (32) 4 (20) 
BV+DTIC (n = 22)BV+bendamustine (n = 20) n
Physical health (OARS)   
 ≥3 comorbidities OR ≥1 that significantly interfered with quality of life*, 11 (50) 9 (45) 
Physical function (MOS)   
 Limited a lot for ≥1 of 10 activities* 16 (73) 14 (70) 
 Preexisting PN 4 (25) 5 (36) 
 Patients with ≥1 fall within prior 6 mo 6 (29) 5 (26) 
 Preexisting PN 1 (17) 2 (40) 
Instrumental activities of daily living (OARS)   
 Completely dependent for ≥1 of 7 iADLs* 2 (9) 4 (20) 
Timed “up and go”   
 >13.5 s to complete action§ 9 (41) 14 (70) 
Unintentional weight loss of ≥10% within the past 6 mo 5 (23) 7 (35) 
BOMC test score of >6 7 (32) 4 (20) 

Data are presented as n (%) of patients.

MOS, Medical Outcomes Study; OARS, Older American Resources and Services.

*

Patient reported.

Thirteen specific comorbidities plus eyesight and hearing (only if fair to totally blind/totally deaf).

Patients with results: n = 21 (BV plus DTIC) and n = 19 (BV plus bendamustine).

§

Stand up from chair, walk 3 m, turn, walk back, and sit down.

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