Subject demographic data
| Subject ID . | Age (years) . | Sex . | Race . | Age at diagnosis . | Previous treatment type . | Dosing cohort, U/kg . | Platelet levels at screening (109/L) . | LDH levels at screening (U/L) . |
|---|---|---|---|---|---|---|---|---|
| 1 | 22 | F | White | 15 | Prophylaxis | 5 | 106* | 294* |
| 2 | 28 | M | White | 24 | On Demand | 5 | 166 | 136 |
| 3 | 35 | M | White | 29 | Prophylaxis | 20 | 154 | 170 |
| 4 | 21 | F | Asian | <1 | Prophylaxis | 40 | 167 | 151 |
| 5 | 24 | F | Asian | 17 | Prophylaxis | 20 | 220 | 142 |
| 6 | 25 | M | White | 2 | Prophylaxis | 40 | 190† | 159 |
| 7 | 33 | F | White | 20 | Prophylaxis | 40 | 223 | 165 |
| 8 | 32 | F | White | 10 | On Demand | 40 | 221 | 146 |
| 9 | 40 | M | White | 16 | Prophylaxis | 40 | 216 | 125 |
| 10 | 41 | F | White | 19 | On Demand | 5 | 348 | 130 |
| 11 | 39 | F | White | 36 | Prophylaxis | 20 | 252 | 259* |
| 12 | 16 | M | White | 14 | Prophylaxis | 40 | 214 | 153 |
| 13 | 17 | F | White | <1 | Prophylaxis | 40 | 353 | 140 |
| 14 | 33 | M | White | 26 | Prophylaxis | 40 | 273 | 122† |
| 15 | 30 | M | Black | 14 | Prophylaxis | 40 | 297 | 185 |
| Subject ID . | Age (years) . | Sex . | Race . | Age at diagnosis . | Previous treatment type . | Dosing cohort, U/kg . | Platelet levels at screening (109/L) . | LDH levels at screening (U/L) . |
|---|---|---|---|---|---|---|---|---|
| 1 | 22 | F | White | 15 | Prophylaxis | 5 | 106* | 294* |
| 2 | 28 | M | White | 24 | On Demand | 5 | 166 | 136 |
| 3 | 35 | M | White | 29 | Prophylaxis | 20 | 154 | 170 |
| 4 | 21 | F | Asian | <1 | Prophylaxis | 40 | 167 | 151 |
| 5 | 24 | F | Asian | 17 | Prophylaxis | 20 | 220 | 142 |
| 6 | 25 | M | White | 2 | Prophylaxis | 40 | 190† | 159 |
| 7 | 33 | F | White | 20 | Prophylaxis | 40 | 223 | 165 |
| 8 | 32 | F | White | 10 | On Demand | 40 | 221 | 146 |
| 9 | 40 | M | White | 16 | Prophylaxis | 40 | 216 | 125 |
| 10 | 41 | F | White | 19 | On Demand | 5 | 348 | 130 |
| 11 | 39 | F | White | 36 | Prophylaxis | 20 | 252 | 259* |
| 12 | 16 | M | White | 14 | Prophylaxis | 40 | 214 | 153 |
| 13 | 17 | F | White | <1 | Prophylaxis | 40 | 353 | 140 |
| 14 | 33 | M | White | 26 | Prophylaxis | 40 | 273 | 122† |
| 15 | 30 | M | Black | 14 | Prophylaxis | 40 | 297 | 185 |