Lymphoma development in IgH-hEBI2 and WT mice in different age groups
| Lineage . | Age range, mo . | n . | % Splenomegaly (no. of mice) . |
|---|---|---|---|
| WT | >18 | 70 | 9 (6) |
| IgH-hEBI2 | <12 | 23 | 4 (1) |
| 12-18 | 30 | 30 (9) | |
| >18 | 41 | 90 (37)* |
| Lineage . | Age range, mo . | n . | % Splenomegaly (no. of mice) . |
|---|---|---|---|
| WT | >18 | 70 | 9 (6) |
| IgH-hEBI2 | <12 | 23 | 4 (1) |
| 12-18 | 30 | 30 (9) | |
| >18 | 41 | 90 (37)* |
Splenomegaly was defined as spleen size above 0.2 g.
*P < .05 by Student t test, relative to lymphoma development in WT mice >18 mo. The numbers in parentheses are the number of animals with splenomegaly within that strain and age group.