AEs
| . | Grade . | ||||||
|---|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | ≥3 . | Any grade . | |
| Hematologic toxicity | |||||||
| Neutropenia | 8 | 18 | 58 | 12 | — | 70 | 96 |
| Leukopenia | 10 | 38 | 34 | 2 | — | 36 | 84 |
| Thrombocytopenia | 56 | 22 | 4 | — | — | 4 | 82 |
| Anemia | 36 | 34 | 4 | — | — | 4 | 74 |
| Lymphopenia | — | 16 | 10 | 10 | — | 20 | 36 |
| Nonhematologic toxicity | |||||||
| Fatigue | 30 | 38 | 4 | — | — | 4 | 72 |
| Peripheral neuropathy | 46 | 18 | 4 | — | — | 4 | 68 |
| Diarrhea | 36 | 10 | 2 | — | — | 2 | 48 |
| Nausea/vomiting | 40 | 2 | — | — | — | — | 42 |
| Lung infection | — | 6 | 8 | 2 | — | 10 | 16 |
| Thromboembolic event | 10 | — | — | — | — | — | 10 |
| Dyspnea | 2 | 4 | 2 | — | — | 2 | 8 |
| Insomnia | — | 8 | — | — | — | — | 8 |
| Herpes zoster infection | 2 | 2 | 2 | — | — | 2 | 6 |
| Generalized muscle weakness | — | 6 | — | — | — | — | 6 |
| Dizziness | — | 6 | — | — | — | — | 6 |
| Anxiety | — | — | 4 | — | — | 4 | 4 |
| Edema | — | 2 | 2 | — | — | 2 | 4 |
| Constipation | — | 4 | — | — | — | — | 4 |
| . | Grade . | ||||||
|---|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | ≥3 . | Any grade . | |
| Hematologic toxicity | |||||||
| Neutropenia | 8 | 18 | 58 | 12 | — | 70 | 96 |
| Leukopenia | 10 | 38 | 34 | 2 | — | 36 | 84 |
| Thrombocytopenia | 56 | 22 | 4 | — | — | 4 | 82 |
| Anemia | 36 | 34 | 4 | — | — | 4 | 74 |
| Lymphopenia | — | 16 | 10 | 10 | — | 20 | 36 |
| Nonhematologic toxicity | |||||||
| Fatigue | 30 | 38 | 4 | — | — | 4 | 72 |
| Peripheral neuropathy | 46 | 18 | 4 | — | — | 4 | 68 |
| Diarrhea | 36 | 10 | 2 | — | — | 2 | 48 |
| Nausea/vomiting | 40 | 2 | — | — | — | — | 42 |
| Lung infection | — | 6 | 8 | 2 | — | 10 | 16 |
| Thromboembolic event | 10 | — | — | — | — | — | 10 |
| Dyspnea | 2 | 4 | 2 | — | — | 2 | 8 |
| Insomnia | — | 8 | — | — | — | — | 8 |
| Herpes zoster infection | 2 | 2 | 2 | — | — | 2 | 6 |
| Generalized muscle weakness | — | 6 | — | — | — | — | 6 |
| Dizziness | — | 6 | — | — | — | — | 6 |
| Anxiety | — | — | 4 | — | — | 4 | 4 |
| Edema | — | 2 | 2 | — | — | 2 | 4 |
| Constipation | — | 4 | — | — | — | — | 4 |
Values are reported as percentage of patients. All AEs with attribution of possible, probable, or definite occurring in >1 patient are listed.
—, Not applicable.