Prognostic models for patients with PV
| Prognostic model . | Risk groups and clinical relevance . |
|---|---|
| Conventional thrombosis score (European LeukemiaNet recommendations)70 | |
| At least 1 of the following risk factors: | Low risk: age <60 y AND no history of thrombosis, that is, no risk factors |
| • Age ≥60 y | High risk: age ≥60 y AND/OR history of thrombosis, that is, at least 1 risk factor |
| • Previous thrombosis | Low-risk patients are given low-dose aspirin and undergo regular phlebotomy to keep hematocrit <45%; high-risk patients are given also a cytoreductive treatment |
| IPSS for overall survival in PV78 | |
| Risk factors (weight): | Low risk: 0 (median survival, 28 y) |
| • Age ≥67 y (5 point) | Intermediate risk: 1-2 points (median survival, 19 y) |
| • Age 57-66 y (2 points) | High risk: ≥3 points (median survival, 11 y) |
| • Leukocyte count ≥15 × 109/L (1 point) | |
| • Previous venous thrombosis (1 point) |
| Prognostic model . | Risk groups and clinical relevance . |
|---|---|
| Conventional thrombosis score (European LeukemiaNet recommendations)70 | |
| At least 1 of the following risk factors: | Low risk: age <60 y AND no history of thrombosis, that is, no risk factors |
| • Age ≥60 y | High risk: age ≥60 y AND/OR history of thrombosis, that is, at least 1 risk factor |
| • Previous thrombosis | Low-risk patients are given low-dose aspirin and undergo regular phlebotomy to keep hematocrit <45%; high-risk patients are given also a cytoreductive treatment |
| IPSS for overall survival in PV78 | |
| Risk factors (weight): | Low risk: 0 (median survival, 28 y) |
| • Age ≥67 y (5 point) | Intermediate risk: 1-2 points (median survival, 19 y) |
| • Age 57-66 y (2 points) | High risk: ≥3 points (median survival, 11 y) |
| • Leukocyte count ≥15 × 109/L (1 point) | |
| • Previous venous thrombosis (1 point) |