Concordance between flow cytometric and molecular MRD dataTF3-1
. | Day 15 . | Day 33 . | Day 78 . | Other TP . | Total . | % (Total %) . | |
---|---|---|---|---|---|---|---|
Concordant | |||||||
FCM+/PCR+ | 102 | 47 | 11 | 9 | 169 | 74 | (93) |
FCM−/PCR− | 1 | 5 | 31 | 4 | 41 | 18 | |
Discordant | |||||||
FCM−/PCR+ | 0 | 5 | 5 | 0 | 10 | 4 | (7) |
FCM+/PCR− | 1 | 4 | 2 | 0 | 7 | 3 | |
Total | 104 | 61 | 49 | 13 | 227 | 100 |
. | Day 15 . | Day 33 . | Day 78 . | Other TP . | Total . | % (Total %) . | |
---|---|---|---|---|---|---|---|
Concordant | |||||||
FCM+/PCR+ | 102 | 47 | 11 | 9 | 169 | 74 | (93) |
FCM−/PCR− | 1 | 5 | 31 | 4 | 41 | 18 | |
Discordant | |||||||
FCM−/PCR+ | 0 | 5 | 5 | 0 | 10 | 4 | (7) |
FCM+/PCR− | 1 | 4 | 2 | 0 | 7 | 3 | |
Total | 104 | 61 | 49 | 13 | 227 | 100 |
Only samples in which MRD could clearly be detected by FCM-MRD or samples which had at least 4 × 106 cells acquired were included in the analyses. Based on an LLOQ of 40 events, this allowed a sensitivity of at least 10−5.
TP, time points.