Table 1.

Top 10 most significantly enriched GO terms per cluster

ClusterFDR-corrected PEnrichmentType
Cluster 1: CD62Ldim ↑    
 Extracellular space 4.98E-09 2.43 Component 
 Extracellular region 1.98E-08 2.69 Component 
 Plasma membrane 5.60E-06 1.58 Component 
 Response to organic substance 1.08E-05 1.86 Function 
 Defense response 1.40E-05 1.86 Function 
 Response to external stimulus 1.75E-05 2.07 Function 
 Response to oxygen-containing compound 2.22E-05 2.04 Function 
 Response to external biotic stimulus 2.41E-05 2.25 Function 
 Response to chemical 2.52E-05 1.69 Function 
 Response to biotic stimulus 3.41E-05 2.22 Function 
Cluster 2: CD62Ldim↓    
 Ribonucleoprotein complex 3.72E-07 2.25 Component 
 Nucleic acid binding 1.01E-05 1.61 Function 
 RNA binding 2.02E-05 1.66 Function 
 RNA metabolic process 4.30E-05 1.82 Process 
 Poly(A) RNA binding 9.61E-05 1.7 Function 
 Nucleic acid metabolic process 3.81E-04 1.67 Process 
 Structural constituent of ribosome 9.23E-04 2.99 Function 
 Ribosomal subunit 1.55E-03 2.91 Component 
 mRNA metabolic process 1.82E-03 2.04 Process 
 Translational elongation 2.04E-03 2.89 Process 
Cluster 4: band > segmented > CD62Ldim    
 Ribonucleoprotein complex 1.07E-15 2.34 Component 
 Ribosomal subunit 2.57E-13 3.55 Component 
 RNA metabolic process 4.25E-13 1.89 Process 
 Cotranslational protein targeting to membrane 4.97E-13 3.32 Process 
 SRP-dependent cotranslational protein targeting to membrane 5.26E-13 3.36 Process 
 Protein targeting to ER 7.39E-13 3.28 Process 
 Nucleic acid metabolic process 7.50E-13 1.78 Process 
 Translational initiation 9.36E-13 3.03 Process 
 Protein localization to ER 1.36E-12 3.2 Process 
 Establishment of protein localization to ER 1.54E-12 3.2 Process 
Cluster 6: CD62Ldim> segmented > band    
 Extracellular vesicular exosome 2.32E-04 1.26 Component 
 Extracellular vesicle 2.90E-04 1.26 Component 
 Extracellular membrane-bounded organelle 3.86E-04 1.26 Component 
 Vesicle 5.18E-04 1.23 Component 
 Extracellular region part 5.57E-04 1.24 Component 
 Extracellular organelle 5.80E-04 1.26 Component 
 Membrane-bounded vesicle 8.88E-04 1.25 Component 
 Actin binding 7.31E-03 2.18 Function 
 Negative regulation of Wnt signaling pathway 2.00E-02 2.45 Process 
 Nicotinamide nucleotide metabolic process 2.02E-02 3.72 Process 
ClusterFDR-corrected PEnrichmentType
Cluster 1: CD62Ldim ↑    
 Extracellular space 4.98E-09 2.43 Component 
 Extracellular region 1.98E-08 2.69 Component 
 Plasma membrane 5.60E-06 1.58 Component 
 Response to organic substance 1.08E-05 1.86 Function 
 Defense response 1.40E-05 1.86 Function 
 Response to external stimulus 1.75E-05 2.07 Function 
 Response to oxygen-containing compound 2.22E-05 2.04 Function 
 Response to external biotic stimulus 2.41E-05 2.25 Function 
 Response to chemical 2.52E-05 1.69 Function 
 Response to biotic stimulus 3.41E-05 2.22 Function 
Cluster 2: CD62Ldim↓    
 Ribonucleoprotein complex 3.72E-07 2.25 Component 
 Nucleic acid binding 1.01E-05 1.61 Function 
 RNA binding 2.02E-05 1.66 Function 
 RNA metabolic process 4.30E-05 1.82 Process 
 Poly(A) RNA binding 9.61E-05 1.7 Function 
 Nucleic acid metabolic process 3.81E-04 1.67 Process 
 Structural constituent of ribosome 9.23E-04 2.99 Function 
 Ribosomal subunit 1.55E-03 2.91 Component 
 mRNA metabolic process 1.82E-03 2.04 Process 
 Translational elongation 2.04E-03 2.89 Process 
Cluster 4: band > segmented > CD62Ldim    
 Ribonucleoprotein complex 1.07E-15 2.34 Component 
 Ribosomal subunit 2.57E-13 3.55 Component 
 RNA metabolic process 4.25E-13 1.89 Process 
 Cotranslational protein targeting to membrane 4.97E-13 3.32 Process 
 SRP-dependent cotranslational protein targeting to membrane 5.26E-13 3.36 Process 
 Protein targeting to ER 7.39E-13 3.28 Process 
 Nucleic acid metabolic process 7.50E-13 1.78 Process 
 Translational initiation 9.36E-13 3.03 Process 
 Protein localization to ER 1.36E-12 3.2 Process 
 Establishment of protein localization to ER 1.54E-12 3.2 Process 
Cluster 6: CD62Ldim> segmented > band    
 Extracellular vesicular exosome 2.32E-04 1.26 Component 
 Extracellular vesicle 2.90E-04 1.26 Component 
 Extracellular membrane-bounded organelle 3.86E-04 1.26 Component 
 Vesicle 5.18E-04 1.23 Component 
 Extracellular region part 5.57E-04 1.24 Component 
 Extracellular organelle 5.80E-04 1.26 Component 
 Membrane-bounded vesicle 8.88E-04 1.25 Component 
 Actin binding 7.31E-03 2.18 Function 
 Negative regulation of Wnt signaling pathway 2.00E-02 2.45 Process 
 Nicotinamide nucleotide metabolic process 2.02E-02 3.72 Process 

ER, endoplasmic reticulum; FDR, false-discovery rate; SRP, signal recognition particle.

View Large
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal