Source of clinical samples
Sample no. . | Sample ID . | Source . | Sex . | Stage . | FISH/t(9:22) . | Figures . |
---|---|---|---|---|---|---|
1 | Spirit CML 0762 | PB | M | CP | ND | 1, 2, 5 |
2 | CML 339 | Leukapheresis | F | CP | + | 2, 4, 5 |
3 | CML 340 | Leukapheresis | M | CP | +* | 4, 5 |
4 | CML 341 (Fresh) | Leukapheresis | M | CP | +* | 1, 2 |
5 | CML 378 | Leukapheresis | F | CP | + | 1, 2 |
6 | CML 381 | Leukapheresis | F | CP | + | 1, 2 |
7 | CML 385 | Leukapheresis | M | CP | +* | 1, 2 |
8 | CML 388 | Leukapheresis | F | CP | +* | 1, 2 |
9 | CML 411 (Fresh) | PB | F | CP | ND | 4, 5 |
10 | CML 412 (Fresh) | Leukapheresis | M | CP | ND | 2, 4, 5 |
11 | CML 441 | Leukapheresis | M | CP | + | 2 |
12 | CML 442 | PB | F | CP | + | 4, 5 |
13 | CML 450 | PB | M | CP | + | 5 |
14 | CML 452 | Leukapheresis | M | CP | + | 2 |
15 | CML 454 (Fresh) | Leukapheresis | M | CP | ND | 3 |
16 | CML 456 | Leukapheresis | F | CP | ND | 3 |
17 | CML 457 (Fresh) | PB | M | CP | ND | 3, 4 |
18 | CML 459 | Leukapheresis | M | CP | ND | 3 |
19 | CML 460 (Fresh) | Leukapheresis | F | CP | ND | 1, 3, 4 |
20 | CML 461 (Fresh) | Leukapheresis | F | CP | ND | 3, 5 |
Sample no. . | Sample ID . | Source . | Sex . | Stage . | FISH/t(9:22) . | Figures . |
---|---|---|---|---|---|---|
1 | Spirit CML 0762 | PB | M | CP | ND | 1, 2, 5 |
2 | CML 339 | Leukapheresis | F | CP | + | 2, 4, 5 |
3 | CML 340 | Leukapheresis | M | CP | +* | 4, 5 |
4 | CML 341 (Fresh) | Leukapheresis | M | CP | +* | 1, 2 |
5 | CML 378 | Leukapheresis | F | CP | + | 1, 2 |
6 | CML 381 | Leukapheresis | F | CP | + | 1, 2 |
7 | CML 385 | Leukapheresis | M | CP | +* | 1, 2 |
8 | CML 388 | Leukapheresis | F | CP | +* | 1, 2 |
9 | CML 411 (Fresh) | PB | F | CP | ND | 4, 5 |
10 | CML 412 (Fresh) | Leukapheresis | M | CP | ND | 2, 4, 5 |
11 | CML 441 | Leukapheresis | M | CP | + | 2 |
12 | CML 442 | PB | F | CP | + | 4, 5 |
13 | CML 450 | PB | M | CP | + | 5 |
14 | CML 452 | Leukapheresis | M | CP | + | 2 |
15 | CML 454 (Fresh) | Leukapheresis | M | CP | ND | 3 |
16 | CML 456 | Leukapheresis | F | CP | ND | 3 |
17 | CML 457 (Fresh) | PB | M | CP | ND | 3, 4 |
18 | CML 459 | Leukapheresis | M | CP | ND | 3 |
19 | CML 460 (Fresh) | Leukapheresis | F | CP | ND | 1, 3, 4 |
20 | CML 461 (Fresh) | Leukapheresis | F | CP | ND | 3, 5 |
CP, chronic phase; ND, not determined; PB, peripheral blood.
CD34+CD38− CML LSCs were also confirmed to be Ph+ by fluorescence in situ hybridization after sorting.