Table 3.

Description of studies using nonvisual method for iPET interpretation

ReferencesDLBCL pts (n)Median ageType of studyTreatmentNb of cycles of chemotherapy before iTEPiTEP analysis methodiTEP-driven
Lin et al20  92 54 Multicentric prospective CHOP or ACVBP ± R Visual and SUV-based centrally No 
Itti et al21  80 53 Multicentric prospective CHOP or ACVBP ± R Visual and SUV-based centrally No 
Casasnovas et al13,25  113 46, all patients <60 y Multicentric prospective R-CHOP or R-ACVBP 2 and 4 Visual centrally reviewed in real-time IHP and ΔSUVmax Yes, according to visual result but not to D5Smax or ΔSUV 
Lanic et al33  57 GC: 30; non-GC: 27 65 Monocentric retrospective R-CHOP or R-CHOP-like 3 or 4 Visual and ΔSUV (70%) local No 
Safar et al22  85 (subgroup analysis) 59 Multicentric prospective R-CHOP or R-ACVBP ΔSUV central No 
Pregno et al50  88 55 Multicentric retrospective R-CHOP-2/14 After 2 (n = 58); after 3 (n = 9); after 4 (n = 21) Deauville scale and ΔSUV (n = 46) central review No 
Nols et al51  73 60 Bicentric retrospective R-CHOP or R-ACVBP After 3 cycles (n = 13) or 4 (n = 60) Deauville and ΔSUV local No 
Lee et al 50 DLBCL out of 61 57 Monocentric prospective R-CHOP Semiquantitative based on SUVmax local No 
Mylan et al 112 62 Multicentric prospective R-CHOP IHP and Deauville scale No 
Mamot et al23  138 GC: 34%; non-GC: 66% 58.4 Multicentric retrospective for Deauville and ΔSUV R-CHOP-14 Central for Deauville and ΔSUV No 
ReferencesDLBCL pts (n)Median ageType of studyTreatmentNb of cycles of chemotherapy before iTEPiTEP analysis methodiTEP-driven
Lin et al20  92 54 Multicentric prospective CHOP or ACVBP ± R Visual and SUV-based centrally No 
Itti et al21  80 53 Multicentric prospective CHOP or ACVBP ± R Visual and SUV-based centrally No 
Casasnovas et al13,25  113 46, all patients <60 y Multicentric prospective R-CHOP or R-ACVBP 2 and 4 Visual centrally reviewed in real-time IHP and ΔSUVmax Yes, according to visual result but not to D5Smax or ΔSUV 
Lanic et al33  57 GC: 30; non-GC: 27 65 Monocentric retrospective R-CHOP or R-CHOP-like 3 or 4 Visual and ΔSUV (70%) local No 
Safar et al22  85 (subgroup analysis) 59 Multicentric prospective R-CHOP or R-ACVBP ΔSUV central No 
Pregno et al50  88 55 Multicentric retrospective R-CHOP-2/14 After 2 (n = 58); after 3 (n = 9); after 4 (n = 21) Deauville scale and ΔSUV (n = 46) central review No 
Nols et al51  73 60 Bicentric retrospective R-CHOP or R-ACVBP After 3 cycles (n = 13) or 4 (n = 60) Deauville and ΔSUV local No 
Lee et al 50 DLBCL out of 61 57 Monocentric prospective R-CHOP Semiquantitative based on SUVmax local No 
Mylan et al 112 62 Multicentric prospective R-CHOP IHP and Deauville scale No 
Mamot et al23  138 GC: 34%; non-GC: 66% 58.4 Multicentric retrospective for Deauville and ΔSUV R-CHOP-14 Central for Deauville and ΔSUV No 
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