Table 4.

Authors’ recommendations for management of CRT

PreventionDiagnosisTreatment
Place CVAD in subclavian > jugular > femoral insertion site. Ultrasound to confirm suspected thrombosis. Anticoagulation for 3 mo or until CVAD removed (whichever is longer). 
Place port > Hickman > PICC. No ultrasound surveillance. Thrombolysis for limb-threatening CRT or severe symptoms and failure to respond to AC. 
Place smallest caliber catheter necessary. CT (or MRI) venography to confirm suspected thrombosis in patients with negative venous ultrasound. CVAD removal if AC contraindicated or infected or no longer needed (add AC if contraindication resolves). 
Place catheter tip at SVC-RA junction.  Avoid SVC filter use. 
Do not use anticoagulant thromboprophylaxis.  Graduated compression garment for symptomatic upper extremity PTS but not PTS prevention. 
PreventionDiagnosisTreatment
Place CVAD in subclavian > jugular > femoral insertion site. Ultrasound to confirm suspected thrombosis. Anticoagulation for 3 mo or until CVAD removed (whichever is longer). 
Place port > Hickman > PICC. No ultrasound surveillance. Thrombolysis for limb-threatening CRT or severe symptoms and failure to respond to AC. 
Place smallest caliber catheter necessary. CT (or MRI) venography to confirm suspected thrombosis in patients with negative venous ultrasound. CVAD removal if AC contraindicated or infected or no longer needed (add AC if contraindication resolves). 
Place catheter tip at SVC-RA junction.  Avoid SVC filter use. 
Do not use anticoagulant thromboprophylaxis.  Graduated compression garment for symptomatic upper extremity PTS but not PTS prevention. 

AC, anticoagulation; CT, computed tomographic; MRI, magnetic resonance imaging; RA, right atrium.

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