Table 3.

Quantified prothrombotic factor group comparisons

PVIAISControlP
MeanSE95% CIMeanSE95% CIMeanSE95% CI
PT, s 11.8 0.12 10.3-13.3 11.3 0.09 10.1-12.6 11.9 0.10 10.6-13.5 <.001* 
INR 1.0 0.01 0.9-1.1 1.0 0.01 0.9-1.1 1.1 0.01 1.0-1.2 <.001* 
PTT, s 31.9 0.42 27.9-37.7 31.6 0.39 27.1-38.0 32.8 0.58 28.3-37.5 .18 
Fibrinogen, g/L 2.5 0.07 1.8-3.3 2.5 0.07 1.7-3.8 2.4 0.06 1.7-3.3 .51 
Antithrombin, U/mL 1.06 0.020 0.88-1.28 1.09 0.016 0.86-1.30 1.03 0.013 0.86-1.21 .018* 
Protein C, U/mL 0.87 0.027 0.63-1.24 0.87 0.025 0.51-1.22 0.87 0.025 0.52-1.27 .99 
Protein S activity, U/mL 0.85 0.022 0.57-1.13 0.86 0.020 0.60-1.20 0.87 0.019 0.64-1.11 .83 
Protein S free, U/mL 0.86 0.021 0.60-1.10 0.85 0.018 0.55-1.09 0.83 0.016 0.63-1.10 .48 
Factor VIII, U/mL 1.04 0.046 0.58-1.69 1.00 0.032 0.64-1.47 1.00 0.034 0.60-1.53 .72 
Factor IX, U/mL 0.77 0.018 0.60-1.01 0.80 0.023 0.54-1.17 0.76 0.018 0.54-1.07 .32 
Factor XI, U/mL 1.00 0.037 0.62-1.39 1.02 0.033 0.69-1.58 1.15 0.032 0.77-1.57 .004* 
Lp(a), g/L 0.24 0.040 0.00-0.69 0.24 0.037 0.00-0.91 0.23 0.039 0.00-0.73 .989 
PVIAISControlP
MeanSE95% CIMeanSE95% CIMeanSE95% CI
PT, s 11.8 0.12 10.3-13.3 11.3 0.09 10.1-12.6 11.9 0.10 10.6-13.5 <.001* 
INR 1.0 0.01 0.9-1.1 1.0 0.01 0.9-1.1 1.1 0.01 1.0-1.2 <.001* 
PTT, s 31.9 0.42 27.9-37.7 31.6 0.39 27.1-38.0 32.8 0.58 28.3-37.5 .18 
Fibrinogen, g/L 2.5 0.07 1.8-3.3 2.5 0.07 1.7-3.8 2.4 0.06 1.7-3.3 .51 
Antithrombin, U/mL 1.06 0.020 0.88-1.28 1.09 0.016 0.86-1.30 1.03 0.013 0.86-1.21 .018* 
Protein C, U/mL 0.87 0.027 0.63-1.24 0.87 0.025 0.51-1.22 0.87 0.025 0.52-1.27 .99 
Protein S activity, U/mL 0.85 0.022 0.57-1.13 0.86 0.020 0.60-1.20 0.87 0.019 0.64-1.11 .83 
Protein S free, U/mL 0.86 0.021 0.60-1.10 0.85 0.018 0.55-1.09 0.83 0.016 0.63-1.10 .48 
Factor VIII, U/mL 1.04 0.046 0.58-1.69 1.00 0.032 0.64-1.47 1.00 0.034 0.60-1.53 .72 
Factor IX, U/mL 0.77 0.018 0.60-1.01 0.80 0.023 0.54-1.17 0.76 0.018 0.54-1.07 .32 
Factor XI, U/mL 1.00 0.037 0.62-1.39 1.02 0.033 0.69-1.58 1.15 0.032 0.77-1.57 .004* 
Lp(a), g/L 0.24 0.040 0.00-0.69 0.24 0.037 0.00-0.91 0.23 0.039 0.00-0.73 .989 

Mean, standard error, and 95% CI for each continuous variable outcome are shown for PIV, AIS (comprising NAIS and APPIS), and controls. P value reflects significance of the original analysis of variance without correction for multiple comparisons.

INR, international normalized ratio; PT prothrombin time; PTT partial thromboplastin time.

*

Significant pairwise difference.

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