Summary of patients’ characteristics at baseline
| Patients characteristics . | LNH2007-3B (n = 89) . | GOELAMS 02.03 (n = 19) . | All . |
|---|---|---|---|
| Men/women, n | 56/33 | 7/12 | 63/45 |
| Age, y | 47 [35-55] | 54 [44-57] | 49 [35-56] |
| Weight, kg | 74 [63-83] | 71 [58-80] | 73.5 [63.0-82.2] |
| Body surface area, m2 | 1.88 [1.74-2.03] | 1.80 [1.65-1.88] | 1.85 [1.68-2.00] |
| Ann Arbor stage, n (%) | |||
| I/II | 3 (3) | 19 (100) | 22 (20) |
| III/IV | 86 (97) | 0 (0) | 86 (80) |
| IPI, n (%) | |||
| 0 | 0 (0) | 15 (79) | 15 (14) |
| 1-2 | 29 (33) | 4 (21) | 33 (31) |
| 3-4 | 60 (67) | 0 (0) | 60 (55) |
| Associated chemotherapy | |||
| CHOP, n (%) | 50 (56) | 19 (100) | 69 (64) |
| ACVBP, n (%) | 39 (44) | 0 | 39 (36) |
| TMTV0, cm3 | 461 [164-796] | 11.8 [4.0-30.8] | 313.5 [83.2-670.7] |
| Baseline lymphocytes, Giga/L | 12.9 [7.3-21.0] | 1.7 [1.4-2.0] | 9.5 [4.0-16.9] |
| CMR, n (%) | 41/88 (47) | 8/9 (89) | 49/97 (50.5) |
| AUC1, mg × h per liter | 9 497 [8 920-10 250] | 16 040 [10 640-20 940] | 9 743 [8 967-10 800] |
| Non-CMR, n (%) | 47/88 (53) | 1/9 (11) | 48/97 (49.5) |
| AUC1, mg × h per liter | 8 730 [7 973-9 592] | 9 493 | 8 733 [7 989-9 577] |
| Patients characteristics . | LNH2007-3B (n = 89) . | GOELAMS 02.03 (n = 19) . | All . |
|---|---|---|---|
| Men/women, n | 56/33 | 7/12 | 63/45 |
| Age, y | 47 [35-55] | 54 [44-57] | 49 [35-56] |
| Weight, kg | 74 [63-83] | 71 [58-80] | 73.5 [63.0-82.2] |
| Body surface area, m2 | 1.88 [1.74-2.03] | 1.80 [1.65-1.88] | 1.85 [1.68-2.00] |
| Ann Arbor stage, n (%) | |||
| I/II | 3 (3) | 19 (100) | 22 (20) |
| III/IV | 86 (97) | 0 (0) | 86 (80) |
| IPI, n (%) | |||
| 0 | 0 (0) | 15 (79) | 15 (14) |
| 1-2 | 29 (33) | 4 (21) | 33 (31) |
| 3-4 | 60 (67) | 0 (0) | 60 (55) |
| Associated chemotherapy | |||
| CHOP, n (%) | 50 (56) | 19 (100) | 69 (64) |
| ACVBP, n (%) | 39 (44) | 0 | 39 (36) |
| TMTV0, cm3 | 461 [164-796] | 11.8 [4.0-30.8] | 313.5 [83.2-670.7] |
| Baseline lymphocytes, Giga/L | 12.9 [7.3-21.0] | 1.7 [1.4-2.0] | 9.5 [4.0-16.9] |
| CMR, n (%) | 41/88 (47) | 8/9 (89) | 49/97 (50.5) |
| AUC1, mg × h per liter | 9 497 [8 920-10 250] | 16 040 [10 640-20 940] | 9 743 [8 967-10 800] |
| Non-CMR, n (%) | 47/88 (53) | 1/9 (11) | 48/97 (49.5) |
| AUC1, mg × h per liter | 8 730 [7 973-9 592] | 9 493 | 8 733 [7 989-9 577] |
Results are given as median [interquartile range].