Table 3.

Replication of SNPs associated with development of proven/probable IA (n = 439) following hematopoietic stem cell transplantation by 2 years

GeneSNPGenomeAllelesMAFModelHR95% CIP
PTX3 rs2305619 DNR A/G* 0.47 Recessive 1.33 1.09-1.64 .005 
CLEC7A rs16910526 DNR + PT G/T 0.08 Dominant + wild type 1.49 1.11-2.02 .009 
GeneSNPGenomeAllelesMAFModelHR95% CIP
PTX3 rs2305619 DNR A/G* 0.47 Recessive 1.33 1.09-1.64 .005 
CLEC7A rs16910526 DNR + PT G/T 0.08 Dominant + wild type 1.49 1.11-2.02 .009 

HR, hazard ratio.

*

Minor/major for PTX3 and TLR4 to keep our model consistent with the original articles, given that the opposite alleles were more frequent in our study.

Major/minor.

Dominant in donor, wild type in recipient, with wild type in both as comparison.

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