Table 1.

Clinicopathologic features on presentation and at relapse/refractory disease of 7 patients with NK/T-cell lymphoma treated with pembrolizumab

CaseOn initial presentationAt relapse/refractory disease before pembrolizumab
SexAge, yPrimary sitesMarrowStageSitesECOG scoreMarrowStageHPS
68 Skin of lower limbs, nasal cavities Negative IV Calf skin Negative IE Nil 
49 Nasal cavities, lymph nodes, liver, spleen, bone Negative IV Liver, spleen Positive IV Yes 
38 Nasopharynx Negative IE Nasopharynx, hard palate Positive IV Yes 
50 Liver Positive IV Liver Positive IV Yes 
31 Nasal cavity, nasopharynx, masseter muscle, bone Negative IV Nasal cavity, liver Negative IV Yes 
35 Nasal cavity Negative IE Lung, esophagus Negative IV Nil 
51 Liver, spleen Positive IV Liver Positive IV Yes 
CaseOn initial presentationAt relapse/refractory disease before pembrolizumab
SexAge, yPrimary sitesMarrowStageSitesECOG scoreMarrowStageHPS
68 Skin of lower limbs, nasal cavities Negative IV Calf skin Negative IE Nil 
49 Nasal cavities, lymph nodes, liver, spleen, bone Negative IV Liver, spleen Positive IV Yes 
38 Nasopharynx Negative IE Nasopharynx, hard palate Positive IV Yes 
50 Liver Positive IV Liver Positive IV Yes 
31 Nasal cavity, nasopharynx, masseter muscle, bone Negative IV Nasal cavity, liver Negative IV Yes 
35 Nasal cavity Negative IE Lung, esophagus Negative IV Nil 
51 Liver, spleen Positive IV Liver Positive IV Yes 

ECOG, Eastern Cooperative Oncology Group; HPS, hemophagocytic syndrome.

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