Table 2.

Analysis of trends

Response
Total (n = 99)Unchanged (n = 40)Increased (n = 29)Decrease (n = 30)
Discrepancy of ≥ 10% 42* NR 23 19 
Interval of more than 18 mo 51 11 17 23 
Possible explanation for the change     
 Additional patients 29 NR 12 17 
 Increase in evaluable patients 12 NR 
 Unexplained 14 NR 
 Other NR 
Response
Total (n = 99)Unchanged (n = 40)Increased (n = 29)Decrease (n = 30)
Discrepancy of ≥ 10% 42* NR 23 19 
Interval of more than 18 mo 51 11 17 23 
Possible explanation for the change     
 Additional patients 29 NR 12 17 
 Increase in evaluable patients 12 NR 
 Unexplained 14 NR 
 Other NR 
*

Studies with discrepancy irrespective of the time interval.

Studies with time interval greater than 18 months, irrespective of presence of discrepancy.

NR, not relevant.

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