Univariate Cox proportional hazards models for the risk of bleeding death in the first 30 days
| . | No. included (no. of HD) . | HR (95% CI) . | P value . |
|---|---|---|---|
| Age, y* | 1009 (37) | 1.07 (0.89-1.30) | .463 |
| PT, s* | 837 (33) | 1.07 (1.00-1.14) | .054 |
| WBC count, 1000 cells/μL* | 999 (37) | 1.07 (1.03-1.10) | <.001 |
| WBC count (grouped) | |||
| High risk (≥20) | 129 (16) | 5.49 (2.86-10.52) | <.001 |
| Low risk (<20) | 870 (21) | REF | |
| Platelet count, 1000 cells/μL* | 999 (37) | 0.91 (0.81-1.02) | .107 |
| Platelet count (grouped) | |||
| High risk (<30) | 484 (21) | 1.41 (0.74-2.71) | .297 |
| Low risk (≥30) | 515 (16) | REF | |
| Peripheral blast count, 1000 cells/μL* | 870 (34) | 1.12 (1.05-1.19) | <.001 |
| PTT, s* | 882 (37) | 0.95 (0.79-1.15) | .627 |
| Fibrinogen, mg/dL | 861 (35) | 1.00 (1.00-1.00) | .689 |
| Hemoglobin, g/dL* | 996 (37) | 0.54 (0.10-2.83) | .464 |
| Creatinine clearance, mL/min* | 869 (36) | 0.96 (0.86-1.07) | .495 |
| ECOG performance status | |||
| Poor (3-4) | 56 (5) | 2.76 (1.07-7.08) | .035 |
| Good (0-2) | 939 (32) | REF | |
| FAB classification | |||
| M3v | 125 (8) | 2.28 (0.99-5.29) | .054 |
| M3 | 592 (17) | REF |
| . | No. included (no. of HD) . | HR (95% CI) . | P value . |
|---|---|---|---|
| Age, y* | 1009 (37) | 1.07 (0.89-1.30) | .463 |
| PT, s* | 837 (33) | 1.07 (1.00-1.14) | .054 |
| WBC count, 1000 cells/μL* | 999 (37) | 1.07 (1.03-1.10) | <.001 |
| WBC count (grouped) | |||
| High risk (≥20) | 129 (16) | 5.49 (2.86-10.52) | <.001 |
| Low risk (<20) | 870 (21) | REF | |
| Platelet count, 1000 cells/μL* | 999 (37) | 0.91 (0.81-1.02) | .107 |
| Platelet count (grouped) | |||
| High risk (<30) | 484 (21) | 1.41 (0.74-2.71) | .297 |
| Low risk (≥30) | 515 (16) | REF | |
| Peripheral blast count, 1000 cells/μL* | 870 (34) | 1.12 (1.05-1.19) | <.001 |
| PTT, s* | 882 (37) | 0.95 (0.79-1.15) | .627 |
| Fibrinogen, mg/dL | 861 (35) | 1.00 (1.00-1.00) | .689 |
| Hemoglobin, g/dL* | 996 (37) | 0.54 (0.10-2.83) | .464 |
| Creatinine clearance, mL/min* | 869 (36) | 0.96 (0.86-1.07) | .495 |
| ECOG performance status | |||
| Poor (3-4) | 56 (5) | 2.76 (1.07-7.08) | .035 |
| Good (0-2) | 939 (32) | REF | |
| FAB classification | |||
| M3v | 125 (8) | 2.28 (0.99-5.29) | .054 |
| M3 | 592 (17) | REF |
Boldface indicates statistically significant results.
REF, reference level.
HR in terms of 10 unit increase.