Expressed fusion transcripts identified by integrated MPseq/RNAseq in PTCL, NOS
| Case . | Age (years) . | Sex . | Diagnosis . | DNA breakpoints . | Fusion transcript(s) . |
|---|---|---|---|---|---|
| TCL26 | 70 | Male | PTCL, NOS | 19p13.3, 20q11.22 | VAV1 ↔ GSS |
| TCL32 | 72 | Male | PTCL, NOS | None | None |
| TCL40 | 50 | Female | PTCL, NOS | None | None |
| TCL65 | 61 | Male | PTCL, NOS | 3q28, 6p22.3 | ATXN1 → TP63 |
| 1p36.23, 11q24.1 | CRTAM ↔ TNFRSF9 | ||||
| TCL66 | 59 | Male | PTCL, NOS | 16p13.3, 19q13.33 | BAX → TCEB2 |
| 19q13.2, 19q13.33 | GSK3A → ZNF541 | ||||
| 19q13.12, 19q13.43 | LOC100128398 → THAP8 | ||||
| TCL72 | 48 | Male | PTCL, NOS | 5q33.1, 5q33.1 | ANXA6 → RBM22 |
| 19p13.2, 19p13.2 | CARM1 → ZNF627 | ||||
| 1p33, 1p35.3 | PPP1R8 → EFCAB14 | ||||
| 5q21.3, 5q33.3 | ITK → FER | ||||
| 1p35.2, 16q22.3 | PUM1 → ZFHX3 | ||||
| 4p16.3, 4p16.3 | STX18 → ZNF718 | ||||
| TCL75 | 67 | Male | PTCL, NOS | 2q34, 2q34 | IKZF2 → ERBB4 |
| 2q12.3, 2q13 | RANBP2 → LIMS1 | ||||
| TCL80 | 56 | Male | PTCL, NOS | 19p13.2, 19p13.3 | VAV1 ↔ MYO1F |
| TCL81 | 64 | Female | PTCL, NOS | 14q32.13, 14q32.2 | ATG2B → CLMN |
| 1p13.1, 1q23.2 | COPA → CD58 | ||||
| 1p33, 1p34.2 | SZT2 → EFCAB14 | ||||
| TCL84 | 62 | Male | PTCL, NOS | None | None |
| TCL86 | 75 | Male | PTCL, NOS | None | None |
| Case . | Age (years) . | Sex . | Diagnosis . | DNA breakpoints . | Fusion transcript(s) . |
|---|---|---|---|---|---|
| TCL26 | 70 | Male | PTCL, NOS | 19p13.3, 20q11.22 | VAV1 ↔ GSS |
| TCL32 | 72 | Male | PTCL, NOS | None | None |
| TCL40 | 50 | Female | PTCL, NOS | None | None |
| TCL65 | 61 | Male | PTCL, NOS | 3q28, 6p22.3 | ATXN1 → TP63 |
| 1p36.23, 11q24.1 | CRTAM ↔ TNFRSF9 | ||||
| TCL66 | 59 | Male | PTCL, NOS | 16p13.3, 19q13.33 | BAX → TCEB2 |
| 19q13.2, 19q13.33 | GSK3A → ZNF541 | ||||
| 19q13.12, 19q13.43 | LOC100128398 → THAP8 | ||||
| TCL72 | 48 | Male | PTCL, NOS | 5q33.1, 5q33.1 | ANXA6 → RBM22 |
| 19p13.2, 19p13.2 | CARM1 → ZNF627 | ||||
| 1p33, 1p35.3 | PPP1R8 → EFCAB14 | ||||
| 5q21.3, 5q33.3 | ITK → FER | ||||
| 1p35.2, 16q22.3 | PUM1 → ZFHX3 | ||||
| 4p16.3, 4p16.3 | STX18 → ZNF718 | ||||
| TCL75 | 67 | Male | PTCL, NOS | 2q34, 2q34 | IKZF2 → ERBB4 |
| 2q12.3, 2q13 | RANBP2 → LIMS1 | ||||
| TCL80 | 56 | Male | PTCL, NOS | 19p13.2, 19p13.3 | VAV1 ↔ MYO1F |
| TCL81 | 64 | Female | PTCL, NOS | 14q32.13, 14q32.2 | ATG2B → CLMN |
| 1p13.1, 1q23.2 | COPA → CD58 | ||||
| 1p33, 1p34.2 | SZT2 → EFCAB14 | ||||
| TCL84 | 62 | Male | PTCL, NOS | None | None |
| TCL86 | 75 | Male | PTCL, NOS | None | None |
→, gene direction of fusion transcript; ↔, reciprocal fusion transcript also present.