Univariate analysis
End points . | 10/10 HLA match group . | P value . | 9/10 HLA match group . | P value . | 8/10 HLA match group . | P value . | |||
---|---|---|---|---|---|---|---|---|---|
MICA-129 Matched . | MICA-129 Mismatched . | MICA-129 Matched . | MICA-129 Mismatched . | MICA-129 Matched . | MICA-129 Mismatched . | ||||
OS | .013 | .006 | .082 | ||||||
1 y | 0.62 (0.59-0.65) | 0.50 (0.37-0.67) | 0.52 (0.48-0.57) | 0.33 (0.23-0.48) | 0.47 (0.39-0.57) | 0.23 (0.11-0.50) | |||
3 y | 0.49 (0.46-0.52) | 0.32 (0.20-0.51) | 0.40 (0.36-0.45) | 0.25 (0.16-0.40) | 0.32 (0.24-0.42) | 0.19 (0.08-0.45) | |||
5 y | 0.44 (0.41-0.47) | 0.27 (0.15-0.48) | 0.37 (0.32-0.42) | 0.23 (0.14-0.37) | 0.30 (0.22-0.40) | 0.19 (0.08-0.45) | |||
DFS | .010 | .018 | .019 | ||||||
1 y | 0.55 (0.53-0.58) | 0.37 (0.26-0.55) | 0.46 (0.42-0.51) | 0.26 (0.16-0.40) | 0.41 (0.33-0.51) | 0.09 (0.03-0.35) | |||
3 y | 0.43 (0.40-0.46) | 0.24 (0.14-0.41) | 0.35 (0.31-0.40) | 0.23 (0.14-0.38) | 0.30 (0.22-0.40) | 0.09 (0.03-0.35) | |||
5 y | 0.36 (0.33-0.39) | 0.20 (0.10-0.38) | 0.30 (0.26-0.34) | 0.14 (0.06-0.31) | 0.25 (0.18-0.35) | 0.09 (0.03-0.35) | |||
NRM | .035 | .901 | .105 | ||||||
1 y | 0.26 (0.23-0.28) | 0.37 (0.23-0.51) | 0.31 (0.27-0.35) | 0.33 (0.22-0.46) | 0.38 (0.29-0.47) | 0.63 (0.39-0.80) | |||
3 y | 0.33 (0.30-0.36) | 0.46 (0.30-0.60) | 0.38 (0.34-0.42) | 0.35 (0.23-0.48) | 0.48 (0.38-0.57) | 0.63 (0.39-0.80) | |||
5 y | 0.36 (0.33-0.39) | 0.51 (0.33-0.67) | 0.40 (0.36-0.45) | 0.38 (0.25-0.50) | 0.49 (0.39-0.58) | 0.63 (0.39-0.80) | |||
RI | .411 | .033 | .592 | ||||||
1 y | 0.22 (0.19-0.25) | 0.30 (0.17-0.43) | 0.28 (0.24-0.32) | 0.46 (0.32-0.58) | 0.28 (0.20-0.36) | 0.42 (0.21-0.62) | |||
3 y | 0.29 (0.26-0.32) | 0.38 (0.23-0.54) | 0.33 (0.29-0.38) | 0.46 (0.32-0.58) | 0.35 (0.26-0.44) | 0.42 (0.21-0.62) | |||
5 y | 0.33 (0.30-0.36) | 0.38 (0.23-0.54) | 0.37 (0.32-0.42) | 0.56 (0.39-0.70) | 0.38 (0.29-0.47) | 0.42 (0.21-0.62) | |||
cGVHD incidence | .988 | .324 | .146 | ||||||
1 y | 0.32 (0.28-0.35) | 0.31 (0.15-0.48) | 0.38 (0.32-0.43) | 0.30 (0.15-0.47) | 0.37 (0.25-0.50) | 0.67 (0.30-0.88) | |||
3 y | 0.40 (0.36-0.43) | 0.38 (0.20-0.56) | 0.43 (0.37-0.48) | 0.30 (0.15-0.47) | 0.47 (0.34-0.59) | 0.67 (0.30-0.88) | |||
5 y | 0.40 (0.36-0.43) | 0.38 (0.20-0.56) | 0.45 (0.39-0.50) | 0.38 (0.17-0.60) | 0.47 (0.34-0.59) | NA |
End points . | 10/10 HLA match group . | P value . | 9/10 HLA match group . | P value . | 8/10 HLA match group . | P value . | |||
---|---|---|---|---|---|---|---|---|---|
MICA-129 Matched . | MICA-129 Mismatched . | MICA-129 Matched . | MICA-129 Mismatched . | MICA-129 Matched . | MICA-129 Mismatched . | ||||
OS | .013 | .006 | .082 | ||||||
1 y | 0.62 (0.59-0.65) | 0.50 (0.37-0.67) | 0.52 (0.48-0.57) | 0.33 (0.23-0.48) | 0.47 (0.39-0.57) | 0.23 (0.11-0.50) | |||
3 y | 0.49 (0.46-0.52) | 0.32 (0.20-0.51) | 0.40 (0.36-0.45) | 0.25 (0.16-0.40) | 0.32 (0.24-0.42) | 0.19 (0.08-0.45) | |||
5 y | 0.44 (0.41-0.47) | 0.27 (0.15-0.48) | 0.37 (0.32-0.42) | 0.23 (0.14-0.37) | 0.30 (0.22-0.40) | 0.19 (0.08-0.45) | |||
DFS | .010 | .018 | .019 | ||||||
1 y | 0.55 (0.53-0.58) | 0.37 (0.26-0.55) | 0.46 (0.42-0.51) | 0.26 (0.16-0.40) | 0.41 (0.33-0.51) | 0.09 (0.03-0.35) | |||
3 y | 0.43 (0.40-0.46) | 0.24 (0.14-0.41) | 0.35 (0.31-0.40) | 0.23 (0.14-0.38) | 0.30 (0.22-0.40) | 0.09 (0.03-0.35) | |||
5 y | 0.36 (0.33-0.39) | 0.20 (0.10-0.38) | 0.30 (0.26-0.34) | 0.14 (0.06-0.31) | 0.25 (0.18-0.35) | 0.09 (0.03-0.35) | |||
NRM | .035 | .901 | .105 | ||||||
1 y | 0.26 (0.23-0.28) | 0.37 (0.23-0.51) | 0.31 (0.27-0.35) | 0.33 (0.22-0.46) | 0.38 (0.29-0.47) | 0.63 (0.39-0.80) | |||
3 y | 0.33 (0.30-0.36) | 0.46 (0.30-0.60) | 0.38 (0.34-0.42) | 0.35 (0.23-0.48) | 0.48 (0.38-0.57) | 0.63 (0.39-0.80) | |||
5 y | 0.36 (0.33-0.39) | 0.51 (0.33-0.67) | 0.40 (0.36-0.45) | 0.38 (0.25-0.50) | 0.49 (0.39-0.58) | 0.63 (0.39-0.80) | |||
RI | .411 | .033 | .592 | ||||||
1 y | 0.22 (0.19-0.25) | 0.30 (0.17-0.43) | 0.28 (0.24-0.32) | 0.46 (0.32-0.58) | 0.28 (0.20-0.36) | 0.42 (0.21-0.62) | |||
3 y | 0.29 (0.26-0.32) | 0.38 (0.23-0.54) | 0.33 (0.29-0.38) | 0.46 (0.32-0.58) | 0.35 (0.26-0.44) | 0.42 (0.21-0.62) | |||
5 y | 0.33 (0.30-0.36) | 0.38 (0.23-0.54) | 0.37 (0.32-0.42) | 0.56 (0.39-0.70) | 0.38 (0.29-0.47) | 0.42 (0.21-0.62) | |||
cGVHD incidence | .988 | .324 | .146 | ||||||
1 y | 0.32 (0.28-0.35) | 0.31 (0.15-0.48) | 0.38 (0.32-0.43) | 0.30 (0.15-0.47) | 0.37 (0.25-0.50) | 0.67 (0.30-0.88) | |||
3 y | 0.40 (0.36-0.43) | 0.38 (0.20-0.56) | 0.43 (0.37-0.48) | 0.30 (0.15-0.47) | 0.47 (0.34-0.59) | 0.67 (0.30-0.88) | |||
5 y | 0.40 (0.36-0.43) | 0.38 (0.20-0.56) | 0.45 (0.39-0.50) | 0.38 (0.17-0.60) | 0.47 (0.34-0.59) | NA |
NA, no cases remaining in follow-up.