Table 4.

Recommended triggers for platelet transfusion in critically ill patients

Transfusion indicationThreshold platelet count (×109/L)Strength of recommendationQuality of evidence
Prophylactic transfusion of adult patients 10 Moderate Low 
Before central vein catheter placement 20 Weak Low 
Before elective diagnostic lumbar punction 50 Weak Very low 
Urgent diagnostic lumbar puncture 20 Weak Very low 
Before major elective surgery (excluding neurosurgery) 50 Weak Very low 
Prophylactic transfusion of nonthrombocytopenic patients before cardiopulmonary bypass surgery No transfusion (only in case of bleeding) Weak Very low 
Patients with intracranial hemorrhage and antiplatelet drugs90  No platelet transfusion Moderate Moderate 
Transfusion indicationThreshold platelet count (×109/L)Strength of recommendationQuality of evidence
Prophylactic transfusion of adult patients 10 Moderate Low 
Before central vein catheter placement 20 Weak Low 
Before elective diagnostic lumbar punction 50 Weak Very low 
Urgent diagnostic lumbar puncture 20 Weak Very low 
Before major elective surgery (excluding neurosurgery) 50 Weak Very low 
Prophylactic transfusion of nonthrombocytopenic patients before cardiopulmonary bypass surgery No transfusion (only in case of bleeding) Weak Very low 
Patients with intracranial hemorrhage and antiplatelet drugs90  No platelet transfusion Moderate Moderate 
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