Table 1.

Quantification of the number of α and δ granules in unstimulated and activated whole platelets

No. of seconds of stimulationNo. of plateletsα granules per plateletδ granules per platelet
No.PNo.P
Unstimulated platelets  49 41.6 ± 4.3  8 ± 0.6  
ADP 5 µM 40.6 ± 1.1  8.1 ± 0.3  
 30 13 38.7 ± 1.5  8.2 ± 0.6  
Thrombin 0.1 U/mL 15 30.8 ± 1.4 <.01 5.8 ± 0.5  
 70 17.5 ± 1.2 <.001 2.7 ± 0.6 <.001 
Thrombin 1 U/mL 10 7.5 ± 0.9 <.001 1.3 ± 0.3 <.001 
 70 2.8 ± 0.8 <.001 None detected  
No. of seconds of stimulationNo. of plateletsα granules per plateletδ granules per platelet
No.PNo.P
Unstimulated platelets  49 41.6 ± 4.3  8 ± 0.6  
ADP 5 µM 40.6 ± 1.1  8.1 ± 0.3  
 30 13 38.7 ± 1.5  8.2 ± 0.6  
Thrombin 0.1 U/mL 15 30.8 ± 1.4 <.01 5.8 ± 0.5  
 70 17.5 ± 1.2 <.001 2.7 ± 0.6 <.001 
Thrombin 1 U/mL 10 7.5 ± 0.9 <.001 1.3 ± 0.3 <.001 
 70 2.8 ± 0.8 <.001 None detected  

Values are presented with standard error of the mean. P values were determined by using the two-way analysis of variance to compare each number of α and δ granules to unstimulated platelets.

or Create an Account

Close Modal
Close Modal