Summary of IRRs occurring in ≥2 patients (part 2)
| Event . | Daratumumab 16 mg/kg + lenalidomide/dexamethasone . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Standard infusion (n = 21) . | Shortened infusion (n = 11) . | Total (N = 32) . | ||||||||||
| All grades . | Grade 3 . | All grades . | Grade 3 . | All grades . | Grade 3 . | |||||||
| No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | |
| Any IRR | 10 | 47.6 | 1 | 4.8 | 8 | 72.7 | 1 | 9.1 | 18 | 56.3 | 2 | 6.3 |
| Cough | 3 | 14.3 | 0 | 0 | 5 | 45.5 | 0 | 0 | 8 | 25 | 0 | 0 |
| Allergic rhinitis | 1 | 4.8 | 0 | 0 | 2 | 18.2 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Nausea | 2 | 9.5 | 0 | 0 | 1 | 9.1 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Vomiting | 2 | 9.5 | 0 | 0 | 1 | 9.1 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Dyspnea | 2 | 9.5 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.3 | 0 | 0 |
| Nasal congestion | 2 | 9.5 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.3 | 0 | 0 |
| Event . | Daratumumab 16 mg/kg + lenalidomide/dexamethasone . | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Standard infusion (n = 21) . | Shortened infusion (n = 11) . | Total (N = 32) . | ||||||||||
| All grades . | Grade 3 . | All grades . | Grade 3 . | All grades . | Grade 3 . | |||||||
| No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | |
| Any IRR | 10 | 47.6 | 1 | 4.8 | 8 | 72.7 | 1 | 9.1 | 18 | 56.3 | 2 | 6.3 |
| Cough | 3 | 14.3 | 0 | 0 | 5 | 45.5 | 0 | 0 | 8 | 25 | 0 | 0 |
| Allergic rhinitis | 1 | 4.8 | 0 | 0 | 2 | 18.2 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Nausea | 2 | 9.5 | 0 | 0 | 1 | 9.1 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Vomiting | 2 | 9.5 | 0 | 0 | 1 | 9.1 | 0 | 0 | 3 | 9.4 | 0 | 0 |
| Dyspnea | 2 | 9.5 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.3 | 0 | 0 |
| Nasal congestion | 2 | 9.5 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.3 | 0 | 0 |