Splenectomy outcome results matched with autoantibody and platelet clearance patterns
| Auto-Ab pattern . | Outcome after splenectomy . | Site of platelet clearance (111In labeled) . | ||
|---|---|---|---|---|
| . | . | Spleen . | Liver . | Mixed . |
| Splenectomized patients (56/93 [60.2%]) | ||||
| Auto-Ab negative 26/56 (46.4%) | CR + R | 16 | 1 | 8 |
| NR | 1 | 0 | 0 | |
| Auto-Ab positive 30/56 (53.6%) | CR + R | 17 | 1 | 8 |
| NR | 1 | 2 | 1 | |
| One positive Ab (10/30) | ||||
| GP IIb-IIIa (4/30) | CR + R | 3 | 1 | 0 |
| NR | 0 | 0 | 0 | |
| GP Ib-IX (4/30) | CR + R | 2 | 0 | 1 |
| NR | 0 | 1 | 0 | |
| GP Ia-IIa (2/30) | CR + R | 1 | 0 | 0 |
| NR | 0 | 0 | 1 | |
| Two positive Abs (7/30) | ||||
| GP IIb-IIIa & GP Ib-IX (2/30) | CR + R | 1 | 0 | 1 |
| NR | 0 | 0 | 0 | |
| GP IIb-IIIa & GP Ia-IIa (5/30) | CR + R | 3 | 0 | 2 |
| NR | 0 | 0 | 0 | |
| Three positive Abs (13/30) | ||||
| GP IIb-IIIa, and GP Ia-IIa, and GP Ib-IX | CR + R | 7 | 0 | 4 |
| NR | 1 | 1 | 0 | |
| Auto-Ab pattern . | Outcome after splenectomy . | Site of platelet clearance (111In labeled) . | ||
|---|---|---|---|---|
| . | . | Spleen . | Liver . | Mixed . |
| Splenectomized patients (56/93 [60.2%]) | ||||
| Auto-Ab negative 26/56 (46.4%) | CR + R | 16 | 1 | 8 |
| NR | 1 | 0 | 0 | |
| Auto-Ab positive 30/56 (53.6%) | CR + R | 17 | 1 | 8 |
| NR | 1 | 2 | 1 | |
| One positive Ab (10/30) | ||||
| GP IIb-IIIa (4/30) | CR + R | 3 | 1 | 0 |
| NR | 0 | 0 | 0 | |
| GP Ib-IX (4/30) | CR + R | 2 | 0 | 1 |
| NR | 0 | 1 | 0 | |
| GP Ia-IIa (2/30) | CR + R | 1 | 0 | 0 |
| NR | 0 | 0 | 1 | |
| Two positive Abs (7/30) | ||||
| GP IIb-IIIa & GP Ib-IX (2/30) | CR + R | 1 | 0 | 1 |
| NR | 0 | 0 | 0 | |
| GP IIb-IIIa & GP Ia-IIa (5/30) | CR + R | 3 | 0 | 2 |
| NR | 0 | 0 | 0 | |
| Three positive Abs (13/30) | ||||
| GP IIb-IIIa, and GP Ia-IIa, and GP Ib-IX | CR + R | 7 | 0 | 4 |
| NR | 1 | 1 | 0 | |
Ab, antibody.