ISTH-DIC scoring system
Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC |
If yes, proceed; if no, do not use this algorithm |
Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) |
Score global coagulation test results |
Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) |
Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) |
Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) |
Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) |
Calculate score |
If ≥5, compatible with overt DIC |
Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC |
If yes, proceed; if no, do not use this algorithm |
Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) |
Score global coagulation test results |
Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) |
Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) |
Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) |
Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) |
Calculate score |
If ≥5, compatible with overt DIC |