Table 1

ISTH-DIC scoring system

Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC 
If yes, proceed; if no, do not use this algorithm 
Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) 
Score global coagulation test results 
 Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) 
 Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) 
 Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) 
 Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) 
Calculate score 
If ≥5, compatible with overt DIC 
Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC 
If yes, proceed; if no, do not use this algorithm 
Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) 
Score global coagulation test results 
 Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) 
 Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) 
 Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) 
 Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) 
Calculate score 
If ≥5, compatible with overt DIC 

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