Table 1 Clinical and laboratory data of... | American Society of Hematology

Table 1

Clinical and laboratory data of TTP patients

Serial no.	Age, y	TTP diagnosis	Platelet count, ×10⁹/L	ADAMTS13 activity, %	Relative abundance, AU			LC/MS HNP1+2+3, AU	ELISA HNPs, ng/mL
Serial no.	Age, y	TTP diagnosis	Platelet count, ×10⁹/L	ADAMTS13 activity, %	HNP1	HNP2	HNP3	LC/MS HNP1+2+3, AU	ELISA HNPs, ng/mL
1	42	Initial	16	<5	85.2	16.1	56.8	158.1	3570.0
2	56	Initial	19	<5	4.6	6.0	6.9	17.4	96.7
3	50	Initial	6	<5	0.1	0.03	0.04	0.1	220.1
4	27	Initial	24	5.4	39.8	7.7	21.3	68.8	1071.2
5	84	Initial	30	<5	1.2	2.3	1.3	4.8	67.2
6	38	Initial	10	<5	4.1	4.2	2.0	10.3	156.6
7	38	Initial	15	<5	4.5	4.7	2.6	11.8	61.7
8	28	Initial	7	8	25.3	9.4	12.9	47.6	669.6
9	58	Initial	14	<5	14.8	6.6	0.1	21.4	164.9
10	40	Initial	22	<5	2.2	6.8	15.1	24.1	295.7
11	23	Initial	11	<5	15.3	8.3	0.6	24.2	346.3
12	33	Initial	13	<5	11.6	6.3	3.1	21.0	170.4
13	57	Initial	11	<5	24.4	10.4	16.7	51.5	1136.6
14	28	Initial	38	<5	3.5	3.3	5.9	12.6	300.3
15	42	Initial	16	<5	14.5	6.2	6.2	27.0	240.4
16	44	Relapsed	15	<5	8.4	5.1	3.9	17.4	80.1
17	46	Relapsed	40	<5	9.0	2.6	1.7	13.3	90.3
18	77	Relapsed	11	<5	2.1	1.4	1.1	4.5	58.0
19	40	Relapsed	21	<5	4.9	2.5	1.7	9.1	58.9
Median (range)	42 (23-84)	NA	15 (6-40)	6.7 (<5-8)	8.4 (0.1-85.2)	6.0 (0.03-16.1)	3.1 (0.04-56.8)	17.4 (0.1-158.1)	170.4 (58.0-3570.0)

Serial no.	Age, y	TTP diagnosis	Platelet count, ×10⁹/L	ADAMTS13 activity, %	Relative abundance, AU			LC/MS HNP1+2+3, AU	ELISA HNPs, ng/mL
Serial no.	Age, y	TTP diagnosis	Platelet count, ×10⁹/L	ADAMTS13 activity, %	HNP1	HNP2	HNP3	LC/MS HNP1+2+3, AU	ELISA HNPs, ng/mL
1	42	Initial	16	<5	85.2	16.1	56.8	158.1	3570.0
2	56	Initial	19	<5	4.6	6.0	6.9	17.4	96.7
3	50	Initial	6	<5	0.1	0.03	0.04	0.1	220.1
4	27	Initial	24	5.4	39.8	7.7	21.3	68.8	1071.2
5	84	Initial	30	<5	1.2	2.3	1.3	4.8	67.2
6	38	Initial	10	<5	4.1	4.2	2.0	10.3	156.6
7	38	Initial	15	<5	4.5	4.7	2.6	11.8	61.7
8	28	Initial	7	8	25.3	9.4	12.9	47.6	669.6
9	58	Initial	14	<5	14.8	6.6	0.1	21.4	164.9
10	40	Initial	22	<5	2.2	6.8	15.1	24.1	295.7
11	23	Initial	11	<5	15.3	8.3	0.6	24.2	346.3
12	33	Initial	13	<5	11.6	6.3	3.1	21.0	170.4
13	57	Initial	11	<5	24.4	10.4	16.7	51.5	1136.6
14	28	Initial	38	<5	3.5	3.3	5.9	12.6	300.3
15	42	Initial	16	<5	14.5	6.2	6.2	27.0	240.4
16	44	Relapsed	15	<5	8.4	5.1	3.9	17.4	80.1
17	46	Relapsed	40	<5	9.0	2.6	1.7	13.3	90.3
18	77	Relapsed	11	<5	2.1	1.4	1.1	4.5	58.0
19	40	Relapsed	21	<5	4.9	2.5	1.7	9.1	58.9
Median (range)	42 (23-84)	NA	15 (6-40)	6.7 (<5-8)	8.4 (0.1-85.2)	6.0 (0.03-16.1)	3.1 (0.04-56.8)	17.4 (0.1-158.1)	170.4 (58.0-3570.0)

All patients received plasma exchange therapy. All samples were collected prior to the first therapeutic plasma exchange.