Response rates
| Response . | MPR (n = 211) No. (%) . | CPR (n = 220) No. (%) . | Rd (n = 212) No. (%) . |
|---|---|---|---|
| Overall response rate | 150 (71) | 150 (68) | 157 (74) |
| Complete response | 7 (3) | 1 (0.5) | 6 (3) |
| Very good partial response | 48 (23) | 44 (20) | 65 (31) |
| Partial response | 95 (45) | 105 (48) | 86 (41) |
| Stable disease | 51 (24) | 62 (28) | 49 (23) |
| Not evaluable* | 8 (4) | 3 (1) | 5 (2) |
| Progressive disease | 2 (1) | 5 (2) | 1 (0.5) |
| Median time to response, mo | 2 | 2 | 1.8 |
| Response . | MPR (n = 211) No. (%) . | CPR (n = 220) No. (%) . | Rd (n = 212) No. (%) . |
|---|---|---|---|
| Overall response rate | 150 (71) | 150 (68) | 157 (74) |
| Complete response | 7 (3) | 1 (0.5) | 6 (3) |
| Very good partial response | 48 (23) | 44 (20) | 65 (31) |
| Partial response | 95 (45) | 105 (48) | 86 (41) |
| Stable disease | 51 (24) | 62 (28) | 49 (23) |
| Not evaluable* | 8 (4) | 3 (1) | 5 (2) |
| Progressive disease | 2 (1) | 5 (2) | 1 (0.5) |
| Median time to response, mo | 2 | 2 | 1.8 |
Patients not evaluable for not completing first induction cycle: Rd: 1 sudden death, 1 death not specified, 1 heart failure, 1 medical decision, 1 lost at follow-up; MPR: 4 adverse events (2 fever of unknown origin, 1 not specified, 1 diarrhea and renal failure), 2 lost at follow-up, 1 death as a result of pneumonia, and 1 sudden death; CPR: 1 withdrawal of consent, 1 death as a result of sepsis, and 1 death as a result of atrial fibrillation.