HLA-DPB1 allele frequencies, FDAA scores, FDAllele scores, TCE groups, and rs9277534 SNP
HLA-DPB1* . | Allele frequency (%)† . | N. AA with FDAA score ≥0.69 . | FDAllele score‡ . | TCE group . | Linkage rs9277534 SNP§ . |
---|---|---|---|---|---|
10:01 | 1.66 | 0 | − 0.12 | 1 | G |
09:01 | 0.72 | 0 | 0 | 1 | G |
17:01 | 1.5 | 0 | 0.54 | 1 | A |
14:01 | 1.17 | 1 | 0.95 | 2 | G |
06:01 | 1.83 | 1 | 1.41 | 2 | G |
19:01 | 0.72 | 2 | 1.43 | 2 | G |
03:01 | 10.11 | 2 | 1.82 | 2 | G |
16:01 | 0.52 | 2 | 2.01 | 3 | G |
20:01 | 0.57 | 2 | 2.36 | 3 | G |
13:01 | 1.57 | 3 | 2.29 | 3 | G |
11:01 | 2.29 | 3 | 2.83 | 3 | G |
02:01 | 12.74 | 3 | 2.94 | 3 | A |
02:02 | 0.67 | 3 | 2.95 | 3 | A |
05:01 | 2.05 | 3 | 2.97 | 3 | G |
15:01 | 0.71 | 4 | 3.79 | 3 | G |
04:02 | 11.52 | 4 | 3.89 | 3 | A |
01:01 | 5.06 | 5 | 4.2 | 3 | G |
04:01 | 43.85 | 5 | 4.58 | 3 | A |
23:01 | 0.54 | 5 | 4.58 | 3 | A |
HLA-DPB1* . | Allele frequency (%)† . | N. AA with FDAA score ≥0.69 . | FDAllele score‡ . | TCE group . | Linkage rs9277534 SNP§ . |
---|---|---|---|---|---|
10:01 | 1.66 | 0 | − 0.12 | 1 | G |
09:01 | 0.72 | 0 | 0 | 1 | G |
17:01 | 1.5 | 0 | 0.54 | 1 | A |
14:01 | 1.17 | 1 | 0.95 | 2 | G |
06:01 | 1.83 | 1 | 1.41 | 2 | G |
19:01 | 0.72 | 2 | 1.43 | 2 | G |
03:01 | 10.11 | 2 | 1.82 | 2 | G |
16:01 | 0.52 | 2 | 2.01 | 3 | G |
20:01 | 0.57 | 2 | 2.36 | 3 | G |
13:01 | 1.57 | 3 | 2.29 | 3 | G |
11:01 | 2.29 | 3 | 2.83 | 3 | G |
02:01 | 12.74 | 3 | 2.94 | 3 | A |
02:02 | 0.67 | 3 | 2.95 | 3 | A |
05:01 | 2.05 | 3 | 2.97 | 3 | G |
15:01 | 0.71 | 4 | 3.79 | 3 | G |
04:02 | 11.52 | 4 | 3.89 | 3 | A |
01:01 | 5.06 | 5 | 4.2 | 3 | G |
04:01 | 43.85 | 5 | 4.58 | 3 | A |
23:01 | 0.54 | 5 | 4.58 | 3 | A |
SNP, single nucleotide polymorphism.
*HLA-DPB1 alleles are listed in the order of increasing number of AAs with FDAA scores ≥0.69 (see text).
See as reported in Hollenbach et al.56 The combined frequency of HLA-DPB1 alleles with 3 or more AAs with FDAA scores ≥0.69 is 81% compared with 18.8% for HLA-DPB1 alleles with 2 or less such AAs.
The median FDAllele score in the 19 HLA-DPB1 alleles listed is 2.36.
See as reported in Petersdorf et al.59