Table 2

Studies of TKI therapy for pediatric CML

TKISponsor and collaboratorPhaseYear publishedAuthor and references
Imatinib COG 2004 Champagne33  
Imatinib COG 2012 Champagne34  
Imatinib French 2011 Millot35  
Dasatinib COG 2011 Aplenc36  
Dasatinib BMS/ITCC 2013 Zwaan37  
Dasatinib BMS Unpublished www.clinicaltrials.gov (#NCT00777036)38  
Nilotinib Novartis Unpublished www.clinicaltrials.gov (#NCT01077544) 
Nilotinib Novartis/COG/ITCC Unpublished www.clinicaltrials.gov (#NCT01844765) 
TKISponsor and collaboratorPhaseYear publishedAuthor and references
Imatinib COG 2004 Champagne33  
Imatinib COG 2012 Champagne34  
Imatinib French 2011 Millot35  
Dasatinib COG 2011 Aplenc36  
Dasatinib BMS/ITCC 2013 Zwaan37  
Dasatinib BMS Unpublished www.clinicaltrials.gov (#NCT00777036)38  
Nilotinib Novartis Unpublished www.clinicaltrials.gov (#NCT01077544) 
Nilotinib Novartis/COG/ITCC Unpublished www.clinicaltrials.gov (#NCT01844765) 

BMS, Bristol-Myers Squibb; CML, chronic myelogenous leukemia; COG, Children’s Oncology Group; ITCC, Innovative Therapies for Children with Cancer Consortium.

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