Table 3

Best response after treatment

Response status, n (%)Sequential (n = 118)Alternating (n = 115)P
Overall response rate (greater than or equal to PR) 90 (76) 92 (80) .7 
sCR 20 (17) 20 (17) 1.0 
CR 29 (25) 26 (23) .8 
Very good PR 25 (21) 26 (24) .5 
PR 16 (14) 20 (16) .6 
Stable disease 4 (3) 3 (3) .8 
Progressive disease 16 (14) 16 (14) 1.0 
Response status, n (%)Sequential (n = 118)Alternating (n = 115)P
Overall response rate (greater than or equal to PR) 90 (76) 92 (80) .7 
sCR 20 (17) 20 (17) 1.0 
CR 29 (25) 26 (23) .8 
Very good PR 25 (21) 26 (24) .5 
PR 16 (14) 20 (16) .6 
Stable disease 4 (3) 3 (3) .8 
Progressive disease 16 (14) 16 (14) 1.0 

The best response after treatment is according to International Myeloma Working Group criteria. Eight patients in the sequential arm and 4 patients in the alternating arm were not evaluable for response because they discontinued early before completing the first cycle.

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