Table 1

Baseline characteristics of the patients

Patient characteristicsSequential (n = 118)Alternating (n = 115)
Age, y 75 (65-89) 73 (66-87) 
Age ≥75 y 65 (55%) 52 (45%) 
M protein   
 IgG 52 (44%) 54 (47%) 
 IgA 32 (27%) 35 (30%) 
 Light chain 14 (12%) 10 (9%) 
ISS stage   
 I 21 (18%) 23 (20%) 
 II 44 (37%) 49 (43%) 
 III 35 (30%) 29 (25%) 
Plasma cell bone marrow infiltration >35% 50 (43%) 50 (44%) 
High risk [t(4;14), t(14;16), del17p] by FISH 19 (16%) 13 (11%) 
Patient characteristicsSequential (n = 118)Alternating (n = 115)
Age, y 75 (65-89) 73 (66-87) 
Age ≥75 y 65 (55%) 52 (45%) 
M protein   
 IgG 52 (44%) 54 (47%) 
 IgA 32 (27%) 35 (30%) 
 Light chain 14 (12%) 10 (9%) 
ISS stage   
 I 21 (18%) 23 (20%) 
 II 44 (37%) 49 (43%) 
 III 35 (30%) 29 (25%) 
Plasma cell bone marrow infiltration >35% 50 (43%) 50 (44%) 
High risk [t(4;14), t(14;16), del17p] by FISH 19 (16%) 13 (11%) 

Data are given as number (percentage) or median (interquartile range).

Ig, immunoglobulin; ISS, International Staging System.

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